Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study
…, M Ittiverakul, P Sia-ngam, W Kuntawunginn… - The Lancet Infectious …, 2015 - thelancet.com
Background Dihydroartemisinin-piperaquine has been adopted as first-line artemisinin
combination therapy (ACT) for multidrug-resistant Plasmodium falciparum malaria in Cambodia …
combination therapy (ACT) for multidrug-resistant Plasmodium falciparum malaria in Cambodia …
Ex Vivo Drug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging …
…, TK Heng, N Kong, W Kuntawunginn… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Cambodia's first-line artemisinin combination therapy, dihydroartemisinin-piperaquine (DHA-PPQ),
is no longer sufficiently curative against multidrug-resistant Plasmodium falciparum …
is no longer sufficiently curative against multidrug-resistant Plasmodium falciparum …
Microscopic Plasmodium falciparum Gametocytemia and Infectivity to Mosquitoes in Cambodia
…, S Balasubramanian, W Kuntawunginn… - The Journal of …, 2016 - academic.oup.com
Although gametocytes are essential for malaria transmission, in Africa many falciparum-infected
persons without smear-detectable gametocytes still infect mosquitoes. To see whether …
persons without smear-detectable gametocytes still infect mosquitoes. To see whether …
[HTML][HTML] Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization
…, P Lertsethtakarn, P Gosi, W Kuntawunginn… - Malaria journal, 2020 - Springer
Background High rates of dihydroartemisinin–piperaquine (DHA–PPQ) treatment failures
have been documented for uncomplicated Plasmodium falciparum in Cambodia. The genetic …
have been documented for uncomplicated Plasmodium falciparum in Cambodia. The genetic …
[HTML][HTML] Efficacy of drug treatment for severe melioidosis and eradication treatment of melioidosis: A systematic review and network meta-analysis
…, P Boonyarangka, W Kuntawunginn… - PLOS Neglected …, 2023 - journals.plos.org
Background This systematic review and network meta-analysis (NMA) aimed to compare
the efficacy of all available treatments for severe melioidosis in decreasing hospital mortality …
the efficacy of all available treatments for severe melioidosis in decreasing hospital mortality …
[HTML][HTML] Efficacy of two versus three-day regimens of dihydroartemisinin-piperaquine for uncomplicated malaria in military personnel in northern Cambodia: an open …
…, S Sriwichai, S Chann, W Kuntawunginn… - PLoS …, 2014 - journals.plos.org
Introduction Emerging antimalarial drug resistance in mobile populations remains a significant
public health concern. We compared two regimens of dihydroartemisinin-piperaquine in …
public health concern. We compared two regimens of dihydroartemisinin-piperaquine in …
[HTML][HTML] Repeatability and reproducibility of a handheld quantitative G6PD diagnostic
…, M Wade, M Wojnarski, K Worachet… - PLOS Neglected …, 2022 - journals.plos.org
Background The introduction of novel short course treatment regimens for the radical cure
of Plasmodium vivax requires reliable point-of-care diagnosis that can identify glucose-6-…
of Plasmodium vivax requires reliable point-of-care diagnosis that can identify glucose-6-…
Randomized, double-blind, placebo-controlled clinical trial of a two-day regimen of dihydroartemisinin-piperaquine for malaria prevention halted for concern over …
…, N Buathong, W Kuntawunginn… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Dihydroartemisinin-piperaquine, the current first-line drug for uncomplicated malaria caused
by Plasmodium falciparum and Plasmodium vivax in Cambodia, was previously shown to …
by Plasmodium falciparum and Plasmodium vivax in Cambodia, was previously shown to …
[HTML][HTML] Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial
…, S Sok, S Chann, M Ittiverakul, W Kuntawunginn… - PloS one, 2017 - journals.plos.org
Background Single low dose primaquine (SLD PQ, 0.25mg/kg) is recommended in
combination with artemisinin-based combination therapy (ACT) as a gametocytocide to prevent …
combination with artemisinin-based combination therapy (ACT) as a gametocytocide to prevent …
[HTML][HTML] Plasmodium falciparum phenotypic and genotypic resistance profile during the emergence of Piperaquine resistance in Northeastern Thailand
…, D Utainnam, W Rodkvamtook, W Kuntawunginn… - Scientific Reports, 2021 - nature.com
Malaria remains a public health problem in Thailand, especially along its borders where
highly mobile populations can contribute to persistent transmission. This study aimed to …
highly mobile populations can contribute to persistent transmission. This study aimed to …