The rapid, sensitive and specific detection of SARS-CoV-2 is critical in responding to the
current COVID-19 outbreak. In this proof-of-concept study, we explored the potential of targeted …

Ubiquitin-specific protease 7 (USP7) has been implicated in cancer progression and
neurodevelopment. However, its molecular targets remain poorly characterized. We combined …

Background & Aims Antigen-specific immunotherapy is a promising strategy to treat HBV
infection and hepatocellular carcinoma (HCC). To facilitate killing of malignant and/or infected …

HIV-1 latency results from tightly regulated molecular processes that act at distinct steps of
HIV-1 gene expression. Here we characterize PCI domain-containing 2 (PCID2) protein, a …

It remains challenging in chronic lymphocytic leukemia (CLL) to distinguish between patients
with favorable and unfavorable time-to-first treatment (TTFT). Additionally, the downstream …

Background Notwithstanding advances in the prognostication of chronic lymphocytic
leukemia (CLL), it remains challenging to distinguish between patients with favorable and …

Tumor-positive resection margins are present in up to 23% of head and neck cancer (HNC)
surgeries, as intraoperative techniques for real-time evaluation of the resection margins are …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). The rapid, sensitive and specific diagnosis of SARS-…

Inadequate surgical margins occur frequently in oral squamous cell carcinoma surgery.
Fluorescence molecular imaging (FMI) has been explored for intraoperative margin assessment, …

In most oral cancer patients, surgical treatment includes resection of the primary tumor
combined with excision of lymph nodes (LNs), either for staging or for treatment. All LNs …