To determine the role of CD8 + T cells in controlling simian immunodeficiency virus (SIV)
replication in vivo, we examined the effect of depleting this cell population using an anti-CD8 …

Although cytotoxic T lymphocytes (CTLs) are thought to be involved in the control of human
immunodeficiency virus–type 1 (HIV-1) infection, it has not been possible to demonstrate a …

Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in
animals used as experimental models in biomedical research. Currently, there are numerous …

… ; Jin-Yu Xia designed the whole study, pro-vided guidance and reviewed and submitted
the article. All authors have read and agreed with the published version of the manuscript. …

Background Whether hearing loss is independently associated with accelerated cognitive
decline in older adults is unknown. Methods We studied 1984 older adults (mean age, 77.4 …

Cytotoxic T lymphocytes (CTL) appear to play an important role in the control of human
cytomegalovirus (HCMV) in the normal virus carrier: previous studies have identified peripheral …

Although surface PEGylation of siRNA vectors is effective for preventing protein adsorption
and thereby helps these vectors to evade the reticuloendothelial system (RES) in vivo, it also …

The role of the thymus in HIV-1 pathogenesis remains unclear. We developed an assay to
quantify the number of recent thymic emigrants in blood based on the detection of a major …

The Beijing Climate Center atmospheric general circulation model version 2.0.1 (BCC_AGCM2.0.1)
is described and its performance in simulating the present-day climate is assessed. …

Methods We aimed to prospectively examine individual and joint associations of low muscle
mass and low muscle strength with all-cause mortality in a nationally representative sample. …