Autophagy is an evolutionarily conserved intracellular process and is considered one of the
main catabolism pathways. In the process of autophagy, cells are digested nonselectively or …

MicroRNAs (miRNAs) interfere with translation of specific target mRNAs and are thought to
thereby regulate many cellular processes. Recent studies have suggested that miRNAs might …

Importance of the field: Bone tissue arises from mesenchymal stromal cells (MSCs) differentiated
into the osteoblast lineage by genetic and epigenetic mechanisms. Emerging evidence …

Our study indicates that recombinant adiponectin induced RANKL and inhibited OPG expression
in human osteoblasts through the AdipoR1/p38 MAPK pathway, and these responses …

Adipocytes can highly and specifically express adiponectin, and the adiponectin receptor (AdipoR)
has been detected in bone-forming cells. The present study was undertaken to …

Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in
osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. …

Our recent study showed that miR-2861 promotes osteoblast differentiation by targeting
histone deacetylase 5, resulting in increased runt-related transcription factor 2 (Runx2) protein …

MicroRNAs (miRNAs) play important roles in osteoclastogenesis and bone resorption. However,
no study has investigated the role of miRNA in postmenopausal osteoporosis. Here, we …

MicroRNAs (miRNAs) play crucial roles in bone metabolism. In the present study, we found
that miR‐148a is dramatically upregulated during osteoclastic differentiation of circulating …

A specific bone vessel subtype, strongly positive for CD31 and endomucin (CD31 hi Emcn hi
), is identified as coupling angiogenesis and osteogenesis. The abundance of type CD31 hi …