Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

Decision making has recently emerged as a central theme in neurophysiological studies of
cognition, and experimental and computational work has led to the proposal of a cortical …

Recent physiological studies of alert primates have revealed cortical neural correlates of
key steps in a perceptual decision-making process. To elucidate synaptic mechanisms of …

Gamma rhythms are commonly observed in many brain regions during both waking and sleep
states, yet their functions and mechanisms remain a matter of debate. Here we review the …

Single-neuron recordings from behaving primates have established a link between working
memory processes and information-specific neuronal persistent activity in the prefrontal …

Recent physiological studies using behaving monkeys revealed that, in a two-alternative
forced-choice visual motion discrimination task, reaction time was correlated with ramping of …

The p53 tumour suppressor is a transcription factor that regulates the progression of the cell
through its cycle and cell death (apoptosis) in response to environmental stimuli such as …

Fast neuronal oscillations (gamma, 20–80 Hz) have been observed in the neocortex and
hippocampus during behavioral arousal. Using computer simulations, we investigated the …

Single-neuron activity in the prefrontal cortex (PFC) is tuned to mixtures of multiple task-related
aspects. Such mixed selectivity is highly heterogeneous, seemingly disordered and …

Delay-period activity of prefrontal cortical cells, the neural hallmark of working memory, is
generally assumed to be sustained by reverberating synaptic excitation in the prefrontal …