Mammalian cells fuel their growth and proliferation through the catabolism of two main
substrates: glucose and glutamine. Most of the remaining metabolites taken up by proliferating …

Polycomb genes encode critical regulators of both normal stem cells and cancer stem cells.
A gene signature that includes Polycomb genes and additional genes coregulated with …

The family of myc proto‐oncogenes encodes transcription factors (c‐, N‐, and L‐Myc) that
regulate cell growth and proliferation and are involved in the etiology of diverse cancers. Myc …

Initial studies of the mammalian hSAGA transcriptional coactivator complex identified the
acetyltransferase hGCN5/PCAF as the only known enzymatic subunit. Recently we …

ALDH1A1 enzyme activity induces MDSC expansion and triggers a procancer immune
microenvironment to facilitate breast cancer progression, providing a novel therapeutic …

A new cytotoxic and antiviral cyclic tetrapeptide, asperterrestide A (1), a new alkaloid,
terremide C (2), and a new aromatic butenolide, aspernolide E (3), together with 10 known …

Low sleep duration in adults is correlated with psychiatric and cognitive problems. We
performed for the first time a large-scale analysis of sleep duration in children, and how this …

Hot compression experiments of a Ti55511 titanium alloy are conducted to study the phase
transformation characteristics and dynamic recrystallization (DRX) behavior. It is found that …

The poor drug delivery to cerebral ischemic regions is a key challenge of ischemic stroke
treatment. Inspired by the intriguing blood–brain barrier (BBB)-penetrating ability of 4T1 cancer …

Transition metal phosphides (TMPs) are recognized as such promising supercapacitor
materials for the practical application, due to their superior electrical conductivity and excellent …