Dendritic cell (DC)-mediated cross-presentation of exogenous antigens acquired in the
periphery is critical for the initiation of CD8 + T cell responses. Several DC subsets are described …

INTRODUCTION Human skin provides vital protection from water loss and from external insult
through structural adaptations and interplay with the innate and adaptive immune systems…

The human syndrome of dendritic cell, monocyte, B and natural killer lymphoid deficiency
presents as a sporadic or autosomal dominant trait causing susceptibility to mycobacterial and …

Bone marrow mesenchymal stem cells (MSC) have potent immunosuppressive properties
and have been advocated for therapeutic use in humans. The nature of their suppressive …

Congenital or acquired cellular deficiencies in humans have the potential to reveal much
about normal hematopoiesis and immune function. We show that a recently described …

Dendritic cells (DCs), monocytes, and macrophages are leukocytes with critical roles in
immunity and tolerance. The DC network is evolutionarily conserved; the homologs of human …

Animal models of hematopoietic stem cell transplantation have been used to analyze the
turnover of bone marrow–derived cells and to demonstrate the critical role of recipient antigen-…

The maintenance of appropriate arterial tone is critically important for normal physiological
arterial function. However, the cellular and molecular mechanisms remain poorly defined. …

During gestation the developing human fetus is exposed to a diverse range of potentially
immune-stimulatory molecules including semi-allogeneic antigens from maternal cells 1 , 2 , …

Mesenchymal stromal cells (MSCs) are potent regulators of immune responses largely
through paracrine signaling. MSC secreted extracellular vesicles (MSC-EVs) are increasingly …