Advances in biological and medical technologies have been providing us explosive volumes
of biological and physiological data, such as medical images, electroencephalography, …

Functional enrichment analysis is pivotal for interpreting high-throughput omics data in life
science. It is crucial for this type of tool to use the latest annotation databases for as many …

Combination therapy has shown an obvious efficacy on complex diseases and can greatly
reduce the development of drug resistance. However, even with high-throughput screens, …

Transcriptional enhancers are non-coding segments of DNA that play a central role in the
spatiotemporal regulation of gene expression programs. However, systematically and …

The semantic comparisons of Gene Ontology (GO) annotations provide quantitative ways to
compute similarities between genes and gene groups, and have became important basis for …

… Xiaochen Bo … Xiaochen Bo … Zhongnan Zhang and Xiaochen Bo directed the project
and contributed to manuscript revisions. All Authors read and approved the final manuscript. …

The Cancer Genome Atlas (TCGA) is a publicly funded project that aims to catalog and
discover major cancer-causing genomic alterations with the goal of creating a comprehensive ‘…

Chromatin insulators are DNA elements that regulate the level of gene expression either by
preventing gene silencing through the maintenance of heterochromatin boundaries or by …

We present the ggtreeExtra package for visualizing heterogeneous data with a phylogenetic
tree in a circular or rectangular layout ( https://www.bioconductor.org/packages/ggtreeExtra )…

Background A fused method using a combination of multi-omics data enables a comprehensive
study of complex biological processes and highlights the interrelationship of relevant …