Exosomes are membrane vesicles that mediate intercellular communication by transporting
their molecular cargo from cell to cell. We investigated whether serum levels of exosomal …

Background MicroRNAs (miRNAs) and Twist1-induced epithelial-mesenchymal transition (EMT)
in cancer cell dissemination are well established, but the involvement of long …

Background: Owing to late diagnosis in advanced disease stages, prognosis of patients
with epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of …

Background Long noncoding RNAs (lncRNAs) have been proven to be involved in carcinogenesis
and to be released into peripheral blood. Our objective was to develop a circulating …

MicroRNAs (MiRNAs) have been found to be dysregulated in lung cancer tissues compared
to their matched paracancerous tissues. However, the roles of miRNAs in peripheral blood …

Cancer is characterized by multiple genetic and epigenetic alterations, including a higher
prevalence of mutations of oncogenes and/or tumor suppressors. Mounting evidences have …

Glutamine synthetase (GS) isozymes play critical roles in nitrogen (N) metabolism. However,
the exact relationship between GS and nitrogen use efficiency (NUE) remain unclear. We …

Background Exosomal cargos such as nucleic acids and proteins have been attracting
major interest as promising diagnostic biomarkers of cancers. The aim of this study was to …

Speckle-type Poz protein (SPOP), an E3 ubiquitin ligase adaptor, is the most frequently
mutated gene in prostate cancer. The SPOP-mutated subtype of prostate cancer shows high …

Glutamine synthetase (GS) plays a major role in plant nitrogen metabolism, but the roles of
individual GS isoforms in grains are unknown. Here, the localization and expression of …