Sequencing of 50 human exomes reveals adaptation to high altitude
X Yi, Y Liang, E Huerta-Sanchez, X Jin, ZXP Cuo… - science, 2010 - science.org
Residents of the Tibetan Plateau show heritable adaptations to extreme altitude. We
sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human …
sequenced 50 exomes of ethnic Tibetans, encompassing coding sequences of 92% of human …
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
…, Z Bianba, BM Peter, N Vinckenbosch, YU Liang, X Yi… - Nature, 2014 - nature.com
As modern humans migrated out of Africa, they encountered many new environmental
conditions, including greater temperature extremes, different pathogens and higher altitudes. …
conditions, including greater temperature extremes, different pathogens and higher altitudes. …
Cellular uptake of elastic nanoparticles
A fundamental understanding of cell-nanomaterial interaction is of essential importance to
nanomedicine and safe applications of nanotechnology. Here we investigate the adhesive …
nanomedicine and safe applications of nanotechnology. Here we investigate the adhesive …
agriGO v2. 0: a GO analysis toolkit for the agricultural community, 2017 update
T Tian, Y Liu, H Yan, Q You, X Yi, Z Du… - Nucleic acids …, 2017 - academic.oup.com
The agriGO platform, which has been serving the scientific community for >10 years, specifically
focuses on gene ontology (GO) enrichment analyses of plant and agricultural species. …
focuses on gene ontology (GO) enrichment analyses of plant and agricultural species. …
Generative adversarial network in medical imaging: A review
Generative adversarial networks have gained a lot of attention in the computer vision
community due to their capability of data generation without explicitly modelling the probability …
community due to their capability of data generation without explicitly modelling the probability …
[HTML][HTML] The diploid genome sequence of an Asian individual
Here we present the first diploid genome sequence of an Asian individual. The genome was
sequenced to 36-fold average coverage using massively parallel sequencing technology. …
sequenced to 36-fold average coverage using massively parallel sequencing technology. …
Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer
…, J Xue, T Deng, X Zhou, K Yu, L Deng, M Huang, X Yi… - Nature medicine, 2020 - nature.com
Clustered regularly interspaced short palindromic repeats (CRISPR)–Cas9 editing of
immune checkpoint genes could improve the efficacy of T cell therapy, but the first necessary …
immune checkpoint genes could improve the efficacy of T cell therapy, but the first necessary …
Development and validation of a deep-learning algorithm for the detection of polyps during colonoscopy
…, Y Song, D Zhang, X Yang, L Li, J He, X Yi… - Nature biomedical …, 2018 - nature.com
The detection and removal of precancerous polyps via colonoscopy is the gold standard for
the prevention of colon cancer. However, the detection rate of adenomatous polyps can vary …
the prevention of colon cancer. However, the detection rate of adenomatous polyps can vary …
Anti-PD-1 antibody SHR-1210 combined with apatinib for advanced hepatocellular carcinoma, gastric, or esophagogastric junction cancer: an open-label, dose …
…, G Zhang, C Zhao, Y Zhang, C Chen, Y Wang, X Yi… - Clinical Cancer …, 2019 - AACR
Purpose: This study assessed the safety and efficacy of SHR-1210 (anti-PD-1 antibody) and
apatinib (VEGFR2 inhibitor) as combination therapy in patients with advanced …
apatinib (VEGFR2 inhibitor) as combination therapy in patients with advanced …
[HTML][HTML] Treatment of coronavirus disease 2019 patients with convalescent plasma reveals a signal of significantly decreased mortality
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2, has spread globally, and proven treatments are limited. Transfusion of …
coronavirus 2, has spread globally, and proven treatments are limited. Transfusion of …