Sepsis, a condition caused by severe infections, affects more than 30 million people
worldwide every year and remains the leading cause of death in hospitals 1 , 2 . Moreover, …

Therapies that synergistically stimulate immunogenic cancer cell death (ICD), inflammation
and immune priming are of great interest for cancer immunotherapy. However, even multi-…

Efficient and safe delivery of the CRISPR/Cas system is one of the key challenges for
genome-editing applications in humans. Herein, we designed and synthesized a series of …

Cytokines are important immunotherapeutics with approved drugs for the treatment of human
cancers. However, systemic administration of cytokines often fails to achieve adequate …

Small molecular dye that simultaneously exerts dual PDT/PTT effects as well as florescence
imaging triggered by a single NIR‐II light has never been reported to date. Apart from the …

Messenger RNA (mRNA) therapeutics have been explored to treat various genetic disorders.
Lipid-derived nanomaterials are currently one of the most promising biomaterials that …

Near-infrared (NIR) fluorescent probes are increasingly popular in biological imaging and
sensing, as long-wavelength (650–900 nm) excitation and emission have the advantages of …

Antibodies targeting costimulatory receptors of T cells have been developed for the activation
of T cell immunity in cancer immunotherapy. However, costimulatory molecule expression …

Restoring innate apoptosis and simultaneously inhibiting metastasis by a molecular drug is
an effective cancer therapeutic approach. Herein, a large rigid and V-shaped NIR-II dye, …

Sulfoxide-bridged dimeric BODIPYs were developed as a new class of long-wavelength
photoconvertible fluorophores. Upon visible-light irradiation, a sulfoxide moiety was released to …