User profiles for Xinran Tong
 | Xinran TongWeill Cornell Medical School Verified email at med.cornell.edu Cited by 238 |
Co-prediction of multiple transportation demands based on deep spatio-temporal neural network
Taxi and sharing bike bring great convenience to urban transportation. A lot of efforts have
been made to improve the efficiency of taxi service or bike sharing system by predicting the …
been made to improve the efficiency of taxi service or bike sharing system by predicting the …
Sexual differentiation in human malaria parasites is regulated by competition between phospholipid metabolism and histone methylation
For Plasmodium falciparum, the most widespread and virulent malaria parasite that infects
humans, persistence depends on continuous asexual replication in red blood cells, while …
humans, persistence depends on continuous asexual replication in red blood cells, while …
Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance
We describe noncovalent, reversible asparagine ethylenediamine (AsnEDA) inhibitors of
the Plasmodium falciparum proteasome (Pf20S) β5 subunit that spare all active subunits of …
the Plasmodium falciparum proteasome (Pf20S) β5 subunit that spare all active subunits of …
The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites
Transmission of Plasmodium falciparum and other malaria parasites requires their
differentiation from asexual blood stages into gametocytes, the non-replicative sexual stage …
differentiation from asexual blood stages into gametocytes, the non-replicative sexual stage …
Cool night‐time temperatures induce the expression of CONSTANS and FLOWERING LOCUS T to regulate flowering in Arabidopsis
Day length and ambient temperature are major stimuli controlling flowering time. To understand
flowering mechanisms in more natural conditions, we explored the effect of daily light …
flowering mechanisms in more natural conditions, we explored the effect of daily light …
Disruption of the Plasmodium falciparum Life Cycle through Transcriptional Reprogramming by Inhibitors of Jumonji Demethylases
Little is known about the role of the three Jumonji C (JmjC) enzymes in Plasmodium falciparum
(Pf). Here, we show that JIB-04 and other established inhibitors of mammalian JmjC …
(Pf). Here, we show that JIB-04 and other established inhibitors of mammalian JmjC …
Leptomeningeal metastatic cells adopt two phenotypic states
Background Leptomeningeal metastasis (LM), or spread of cancer cells into the cerebrospinal
fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and …
fluid (CSF), is characterized by a rapid onset of debilitating neurological symptoms and …
Metabolic competition between lipid metabolism and histone methylation regulates sexual differentiation in human malaria parasites
Like most pathogens, malaria parasites balance persistence in the current host with
transmission to the next. For Plasmodium falciparum, the most widespread and virulent human …
transmission to the next. For Plasmodium falciparum, the most widespread and virulent human …
[HTML][HTML] Generation of transmission-competent human malaria parasites with chromosomally-integrated fluorescent reporters
…, G Mlambo, PC Dumoulin, CT Harris, X Tong… - Scientific reports, 2019 - nature.com
Malaria parasites have a complex life cycle that includes specialized stages for transmission
between their mosquito and human hosts. These stages are an understudied part of the …
between their mosquito and human hosts. These stages are an understudied part of the …
Leptomeningeal anti-tumor immunity follows unique signaling principles
Metastasis to the cerebrospinal fluid (CSF)-filled leptomeninges, or leptomeningeal metastasis
(LM), represents a fatal complication of cancer. Proteomic and transcriptomic analyses of …
(LM), represents a fatal complication of cancer. Proteomic and transcriptomic analyses of …