… Wenguang Xu and Xiuying Wen performed the study and contributes in the writing of
manuscript. Ming Xiao, Qijian Mei contributes in the statistical analysis and collected the data. …

ETHNOPHARMACOLOGICAL RELEVANCE: Zhenqing Recipe (ZQR), a Chinese herbal
prescription, is used to improve renal function of patients with diabetic nephropathy. In current …

Aim In this study, we investigated the role and mechanism of Salt-induced kinase 1 (SIK1) in
regulation of hepatic glucose and lipid metabolism in a high-fat food (HFD) and streptozocin …

The regulation of hepatic gluconeogenesis is of great significance to improve insulin
resistance and benefit diabetes therapy. cAMP-Regulated Transcriptional Co-activator 2 (CRTC2) …

Aims To investigate the roles of salt inducible kinase (SIK1) in high glucose-induced triglyceride
accumulation in human hepatoma HepG2 cells as well as in the molecular mechanism …

High glucose levels can induce mesangial cell proliferation and extracellular matrix (ECM)
accumulation through the type I activin receptor-like kinase 5 (ALK5) signaling pathway. Salt-…

Background As a compound Chinese medicine, Zhenqing Recipe (ZQR) has been shown to
ameliorate hyperglycemia, hyperlipidemia, fatty liver and insulin resistance in patients with …

Diabetic nephropathy, a chronic inflammatory disease, is characterized by hyperglycemia-stimulated
pyroptosis of renal tubular epithelial cells. Gambogic acid, a primary component of …

Forkhead box O1 (FOXO1) plays an important role in glucose metabolism at the gene transcription
level. Increased FOXO1 activity results in hyperglycemia by promoting the expression …

Objective: To investigate the association of lipoprotein lipase gene intron 8 polymorphisms
and Essential Hypertension in Han race Chinese. Methods and results: 116 patients with …