User profiles for Xiulai Chen

Xiulai Chen

Jiangnan University
Verified email at jiangnan.edu.cn
Cited by 3363

Engineering redox balance through cofactor systems

X Chen, S Li, L Liu - Trends in biotechnology, 2014 - cell.com
Redox balance plays an important role in the production of enzymes, pharmaceuticals, and
chemicals. To meet the demands of industrial production, it is desirable that microbes …

[HTML][HTML] Light-powered Escherichia coli cell division for chemical production

…, L Guo, C Gao, G Hu, C Ye, J Liu, L Liu, X Chen - Nature …, 2020 - nature.com
Cell division can perturb the metabolic performance of industrial microbes. The C period of
cell division starts from the initiation to the termination of DNA replication, whereas the D …

Engineering Escherichia coli lifespan for enhancing chemical production

L Guo, W Diao, C Gao, G Hu, Q Ding, C Ye, X Chen… - Nature Catalysis, 2020 - nature.com
Industrial chemical production from renewable feedstocks by microbial cell factories provides
a promising avenue towards sustainability. However, the small size of bacterial cells and …

Engineering microorganisms for enhanced CO2 sequestration

G Hu, Y Li, C Ye, L Liu, X Chen - Trends in biotechnology, 2019 - cell.com
Microbial CO 2 sequestration not only provides a green and sustainable approach for
ameliorating global warming but also simultaneously produces biofuels and chemicals. However, …

Light-driven CO2 sequestration in Escherichia coli to achieve theoretical yield of chemicals

…, Z Li, D Ma, C Ye, L Zhang, C Gao, L Liu, X Chen - Nature Catalysis, 2021 - nature.com
CO 2 sequestration engineering is an attractive strategy for achieving carbon- and energy-efficient
bioproduction. However, the efficiency of heterotrophic CO 2 sequestration is limited …

DCEO biotechnology: tools to design, construct, evaluate, and optimize the metabolic pathway for biosynthesis of chemicals

X Chen, C Gao, L Guo, G Hu, Q Luo, J Liu… - Chemical …, 2018 - ACS Publications
Chemical synthesis is a well established route for producing many chemicals on a large
scale, but some drawbacks still exist in this process, such as unstable intermediates, multistep …

Engineering microbial membranes to increase stress tolerance of industrial strains

Y Qi, H Liu, X Chen, L Liu - Metabolic Engineering, 2019 - Elsevier
The microbial membrane serves as a biological barrier that separates the interior of cells
from the external environment, thus playing an important role in tolerance to stress conditions …

[HTML][HTML] Programmable biomolecular switches for rewiring flux in Escherichia coli

…, X Chen, G Hu, C Ye, H Edwards, J Chen… - Nature …, 2019 - nature.com
Synthetic biology aims to develop programmable tools to perform complex functions such as
redistributing metabolic flux in industrial microorganisms. However, development of protein-…

[HTML][HTML] Enhancing biofuels production by engineering the actin cytoskeleton in Saccharomyces cerevisiae

…, G Hu, W Song, J Wu, X Chen, J Chen, W Chen… - Nature …, 2022 - nature.com
Saccharomyces cerevisiae is widely employed as a cell factory for the production of biofuels.
However, product toxicity has hindered improvements in biofuel production. Here, we …

Improving lysine production through construction of an Escherichia coli enzyme‐constrained model

…, C Gao, N Xu, L Zhang, L Liu, X Chen - Biotechnology and …, 2020 - Wiley Online Library
Microbial cell factories are widely used for the production of high‐value chemicals. However,
maximizing production titers is made difficult by the complicated regulatory mechanisms of …