Mitochondrial redox homeostasis, the balance between reactive oxygen species and
antioxidants such as glutathione, plays critical roles in many biological processes, including …

Cancer vaccines hold great promise for improved cancer treatment. However, endosomal
trapping and low immunogenicity of tumour antigens usually limit the efficiency of vaccination …

The evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
highlighted the need for versatile diagnostic assays that can discriminate among emerging …

The accumulation of mitochondrial DNA (mtDNA) mutations in cells is strongly related to
aging-associated diseases. Imaging of single-nucleotide variation (SNV) in mtDNA is crucial for …

CRISPR/Cas9 has already become a powerful tool for genomic manipulation, and further
engineering of the system allows it to be precisely regulated in response to external signals, …

Glioblastoma (GBM) is the most malignant brain tumor with unmet therapeutic demand. The
blood‐brain‐barrier (BBB) and tumor heterogeneity limit the treatment effectiveness of …

Stroke is a lethal cerebral disease with severe sequelae and high mortality. Microglia, the
main immune cell in the cerebrum, possess therapeutic potential for strokes as its specific anti‐…

Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), a long noncoding RNA
(lncRNA) located in the cell nucleus, is a critical regulator of tumor cell migration. Antisense …

G‐quadruplexes (G4s), non‐canonical nucleic acid secondary structure, regulate many
biological functions and are considered potential molecular targets for cancer therapeutics. …

MicroRNAs (miRNAs) play a critical role in multifarious biological processes and being
deemed to be important biomarkers for clinical cancer diagnosis, prognosis, and therapy. Thus, …