User profiles for Xuemei Han

Xuemei Han

- Verified email at ntu.edu.sg - Cited by 2386

Xuemei Han

- Verified email at natureserve.org - Cited by 680

Mass spectrometry for proteomics

X Han, A Aslanian, JR Yates III - Current opinion in chemical biology, 2008 - Elsevier
Mass spectrometry has been widely used to analyze biological samples and has evolved into
an indispensable tool for proteomics research. Our desire to understand the proteome has …

Extending top-down mass spectrometry to proteins with masses greater than 200 kilodaltons

X Han, M Jin, K Breuker, FW McLafferty - Science, 2006 - science.org
For characterization of sequence and posttranslational modifications, molecular and fragment
ion mass data from ionizing and dissociating a protein in the mass spectrometer are far …

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

JC Kuo, X Han, CT Hsiao, JR Yates III… - Nature cell …, 2011 - nature.com
Focal adhesions undergo myosin-II-mediated maturation wherein they grow and change
composition to modulate integrin signalling for cell migration, growth and differentiation. To …

The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions

…, F Halgand, SC Hall, X Han… - Journal of proteome …, 2008 - ACS Publications
Saliva is a body fluid with important functions in oral and general health. A consortium of
three research groups catalogued the proteins in human saliva collected as the ductal …

Favoring the unfavored: selective electrochemical nitrogen fixation using a reticular chemistry approach

HK Lee, CSL Koh, YH Lee, C Liu, IY Phang, X Han… - Science …, 2018 - science.org
Electrochemical nitrogen-to-ammonia fixation is emerging as a sustainable strategy to
tackle the hydrogen- and energy-intensive operations by Haber-Bosch process for ammonia …

Designing surface-enhanced Raman scattering (SERS) platforms beyond hotspot engineering: emerging opportunities in analyte manipulations and hybrid materials

…, YH Lee, CSL Koh, GC Phan-Quang, X Han… - Chemical Society …, 2019 - pubs.rsc.org
Surface-enhanced Raman scattering (SERS) is a molecule-specific spectroscopic technique
with diverse applications in (bio)chemistry, clinical diagnosis and toxin sensing. While …

[HTML][HTML] Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

…, A Nutter, B Shan, E Molokanova, Y Zhang, X Han… - Cell, 2013 - cell.com
Parkinson's disease (PD) is characterized by loss of A9 dopaminergic (DA) neurons in the
substantia nigra pars compacta (SNpc). An association has been reported between PD and …

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

M Gonzalez-Begne, B Lu, X Han… - Journal of proteome …, 2009 - ACS Publications
Human ductal saliva contributes over a thousand unique proteins to whole oral fluids. The
mechanism by which most of these proteins are secreted by salivary glands remains to be …

[PDF][PDF] O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability

HB Ruan, X Han, MD Li, JP Singh, K Qian… - Cell metabolism, 2012 - cell.com
A major cause of hyperglycemia in diabetic patients is inappropriate hepatic gluconeogenesis.
PGC-1α is a master regulator of gluconeogenesis, and its activity is controlled by various …

Report of a mental health survey among Chinese international students at Yale University

X Han, X Han, Q Luo, S Jacobs… - Journal of American …, 2013 - Taylor & Francis
Objective: To examine the prevalence of depression and anxiety symptoms in Chinese
international students, to identify factors that might be associated with these 2 symptom …