The S4 segment comprises part of the voltage sensor in Shaker K+ channels. We have
used a strategy similar to intragenic suppression, but without a genetic selection, to identify …

Delineating neurons that underlie complex behaviors is of fundamental interest. Using
adeno-associated virus 2, we expressed the Drosophila allatostatin receptor in somatostatin (Sst)-…

Alcohol use disorders (AUDs) constitute the most common form of substance abuse. The
development of AUDs involves repeated alcohol use leading to tolerance, alcohol withdrawal …

Shao, Xuesi M. and Jack L. Feldman. Respiratory rhythm generation and synaptic inhibition
of expiratory neurons in pre-Bötzinger complex: differential roles of glycinergic and …

Breathing pattern is postulated to be generated by brainstem neurons. However, determination
of the underlying cellular mechanisms, and in particular the synaptic interactions …

Background Anxiety disorders are the most prevalent mental illnesses in the US and are
estimated to consume one-third of the country’s mental health treatment cost. Although …

Electronic cigarettes or e-cigarettes are the most frequently used tobacco product among
adolescents. Despite the widespread use of e-cigarettes and the known detrimental cardiac …

Electronic cigarettes (e-cigarettes), also known as electronic nicotine delivery systems, are a
popular alternative to conventional nicotine cigarettes, both among smokers and those who …

Calcium influx is crucial for T cell activation and differentiation. The detailed regulation of this
process remains unclear. We report here that golli protein, an alternatively spliced product …

Alzheimer’s disease (AD) is the leading progressive neurodegenerative disorder afflicting
35.6 million people worldwide. There is no therapeutic agent that can slow or stop the …