[HTML][HTML] Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

…, X Guo, Q Li, X Li, W Wang, Y Zhang, J Wang, X Jiang… - Cell research, 2008 - nature.com
Dysregulated expression of microRNAs (miRNAs) in various tissues has been associated with
a variety of diseases, including cancers. Here we demonstrate that miRNAs are present in …

Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3–independent β-catenin degradation

L Topol, X Jiang, H Choi, L Garrett-Beal… - The Journal of cell …, 2003 - rupress.org
Wnts are secreted signaling molecules that can transduce their signals through several different
pathways. Wnt-5a is considered a noncanonical Wnt as it does not signal by stabilizing β…

Wnt/β-catenin signaling is sufficient and necessary for synovial joint formation

X Guo, TF Day, X Jiang, L Garrett-Beal… - Genes & …, 2004 - genesdev.cshlp.org
A critical step in skeletal morphogenesis is the formation of synovial joints, which define the
relative size of discrete skeletal elements and are required for the mobility of vertebrates. We …

AgHalo: a facile fluorogenic sensor to detect drug‐induced proteome stress

…, NP Dunham, Z Gao, K Miao, X Jiang… - Angewandte …, 2017 - Wiley Online Library
Drug‐induced proteome stress that involves protein aggregation may cause adverse effects
and undermine the safety profile of a drug. Safety of drugs is regularly evaluated using …

[HTML][HTML] The identification of novel targets of miR-16 and characterization of their biological functions in cancer cells

…, H Liang, T Deng, K Zhu, S Zhang, N Wang, X Jiang… - Molecular cancer, 2013 - Springer
Background In eukaryotes, miR-16 is an important microRNA (miRNA) that is involved in
numerous biological processes. However, it is not fully understood how miR-16 executes its …

[HTML][HTML] The microbiome–metabolome response in the colon of piglets under the status of weaning stress

X Jiang, N Lu, H Zhao, H Yuan, D Xia… - Frontiers in Microbiology, 2020 - frontiersin.org
Weaning is stressful for piglets involving nutritional, physiological, and psychological
challenges, leading to an increase in the secretion of cortisol, changes in gut microbiome and …

Multiple regulatory modules are required for scale-to-feather conversion

…, J Yan, YC Lai, CS Ng, A Li, X Jiang… - Molecular biology …, 2018 - academic.oup.com
The origin of feathers is an important question in Evo-Devo studies, with the eventual evolution
of vaned feathers which are aerodynamic, allowing feathered dinosaurs and early birds …

Crude fiber modulates the fecal microbiome and steroid hormones in pregnant Meishan sows

X Jiang, N Lu, Y Xue, S Liu, H Lei, W Tu, Y Lu… - General and comparative …, 2019 - Elsevier
The beneficial effects of dietary fiber on the reproductive performance and welfare of sows
have been discussed broadly, but few researches examined the causal changes and the …

[HTML][HTML] miR-16 promotes the apoptosis of human cancer cells by targeting FEAT

H Liang, Z Fu, X Jiang, N Wang, F Wang, X Wang… - BMC cancer, 2015 - Springer
Background Although human cancers have heterogeneous combinations of altered oncogenes,
some crucial genes are universally dysregulated in most cancers. One such gene, FEAT …

[HTML][HTML] Butyric acid regulates progesterone and estradiol secretion via cAMP signaling pathway in porcine granulosa cells

N Lu, M Li, H Lei, X Jiang, W Tu, Y Lu, D Xia - The Journal of Steroid …, 2017 - Elsevier
Butyric acid (BA), one of the short chain fatty acids (SCFAs), has positive actions on the
metabolism, inflammation, etc. However, whether it influences the reproductive physiology and if …