SARS-CoV-2 has caused the COVID-19 pandemic. There is an urgent need for physiological
models to study SARS-CoV-2 infection using human disease-relevant cells. COVID-19 …

There is an urgent need to create novel models using human disease-relevant cells to study
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology and to facilitate …

Recent clinical data have suggested a correlation between coronavirus disease 2019 (COVID-19)
and diabetes. Here, we describe the detection of SARS-CoV-2 viral antigen in …

COVID-19 is a systemic disease involving multiple organs. We previously established a
platform to derive organoids and cells from human pluripotent stem cells to model SARS-CoV-2 …

Paragraph The SARS-CoV-2 virus has caused already over 3.5 million COVID-19 cases
and 250,000 deaths globally. There is an urgent need to create novel models to study SARS-…

Embryonic hematopoiesis is a complex process. Elucidating the mechanism regulating
hematopoietic differentiation from pluripotent stem cells would allow us to establish a strategy to …

It is urgent to develop disease models to dissect mechanisms regulating severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we derive airway organoids …

Genetic studies have identified numerous loci associated with type 2 diabetes (T2D), but the
functional roles of many loci remain unexplored. Here, we engineered isogenic knockout …

Despite advances in promoting axonal regeneration after adult central nervous system injury,
elicitation of a large number of lesion-passing axons reform active synaptic connections …

Inflammatory factors and activation of oncogenes both played critical roles in the development
and progression of human hepatocellular carcinoma (HCC). However, the interplay …