High expression of PD-L1 in tumor cells contributes to tumor immune evasion. However,
whether PD-L1 expression in tumor cells is regulated by the availability of nutrients is unknown. …

Autophagy is an evolutionarily conserved catabolic process that recycles proteins and
organelles in a lysosome-dependent manner and is induced as an alternative source of energy …

Loss of hepatic fructose-1, 6-bisphosphate aldolase B (Aldob) leads to a paradoxical up-regulation
of glucose metabolism to favor hepatocellular carcinogenesis (HCC), but the …

Metabolic reprogramming is a core hallmark of cancer but it remains poorly defined in
hepatocellular carcinogenesis (HCC). Here we show that hepatic aldolase B (Aldob) suppresses …

The well-documented anticarcinogenic properties of natural polyphenolic proanthocyanidins
(OPC) have been primarily attributed to their antioxidant and anti-inflammatory potency. …

Background Short videos on social media are playing an increasingly important role in cancer
health education today. It is important to explore how the actual communication effect of …

Background and Aims Insulin receptor (IR) transduces cell surface signal through
phosphoinositide 3‐kinase (PI3K)–AKT pathways or translocates to the nucleus and binds to the …

Telomere dysfunction is intricately linked to the aging process and stands out as a prominent
cancer hallmark. Here we demonstrate that telomerase activity is differentially regulated in …

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Here,
we identified that increased miR‐23a expression in HCC tissues was associated with worse …

The unstable mechanism of bump of the coal pillar under hard rocks is discussed by using a
cusp catastrophic model. The criterion of rock bursts occurrence and the quantity of roof …