User profiles for Y. H. Grad

Yonatan Grad

Professor of Immunology and Infectious Diseases, Harvard TH Chan School of Public Health
Verified email at hsph.harvard.edu
Cited by 13349

[HTML][HTML] Cross-reactive memory T cells and herd immunity to SARS-CoV-2

M Lipsitch, YH Grad, A Sette, S Crotty - Nature Reviews Immunology, 2020 - nature.com
Immunity is a multifaceted phenomenon. For T cell-mediated memory responses to SARS-CoV-2,
it is relevant to consider their impact both on COVID-19 disease severity and on viral …

Origin and proliferation of multiple-drug resistance in bacterial pathogens

HH Chang, T Cohen, YH Grad… - Microbiology and …, 2015 - Am Soc Microbiol
Many studies report the high prevalence of multiply drug-resistant (MDR) strains. Because
MDR infections are often significantly harder and more expensive to treat, they represent a …

[HTML][HTML] Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination

S Cobey, DB Larremore, YH Grad… - Nature Reviews …, 2021 - nature.com
When vaccines are in limited supply, expanding the number of people who receive some
vaccine, such as by halving doses or increasing the interval between doses, can reduce …

Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period

SM Kissler, C Tedijanto, E Goldstein, YH Grad… - Science, 2020 - science.org
It is urgent to understand the future of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2)
transmission. We used estimates of seasonality, immunity, and cross-immunity …

Model-informed COVID-19 vaccine prioritization strategies by age and serostatus

…, K Reinholt, SM Kissler, M Lipsitch, S Cobey, YH Grad… - Science, 2021 - science.org
Limited initial supply of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine raises the question of how to prioritize available doses. We used a mathematical model …

[HTML][HTML] Viral dynamics of SARS-CoV-2 variants in vaccinated and unvaccinated persons

…, DD Ho, ND Grubaugh, YH Grad - … England Journal of …, 2021 - Mass Medical Soc
Study of SARS-CoV-2 Dynamics in the NBA A SARS-CoV-2 surveillance program
conducted by the National Basketball Association identified 173 newly infected persons. The …

Aggregated mobility data could help fight COVID-19

…, J Chan, M Crosas, F Dominici, U Gasser, YH Grad… - Science, 2020 - science.org
As the coronavirus disease 2019 (COVID-19) pandemic progresses, social distancing has
emerged as an effective measure to restrain the spread of infections. Many people are now …

Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011

YH Grad, M Lipsitch, M Feldgarden… - Proceedings of the …, 2012 - National Acad Sciences
The degree to which molecular epidemiology reveals information about the sources and
transmission patterns of an outbreak depends on the resolution of the technology used and the …

[HTML][HTML] Individual quarantine versus active monitoring of contacts for the mitigation of COVID-19: a modelling study

CM Peak, R Kahn, YH Grad, LM Childs, R Li… - The Lancet Infectious …, 2020 - thelancet.com
Background Voluntary individual quarantine and voluntary active monitoring of contacts are
core disease control strategies for emerging infectious diseases such as COVID-19. Given …

[HTML][HTML] Viral dynamics of acute SARS-CoV-2 infection and applications to diagnostic and public health strategies

…, J Mancell, DD Ho, ND Grubaugh, YH Grad - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 infections are characterized by viral proliferation and clearance phases and
can be followed by low-level persistent viral RNA shedding. The dynamics of viral RNA …