Abrading bulk metal into single atoms
Single-atom catalysts have recently attracted considerable attention because of their highly
efficient metal utilization and unique properties. Finding a green, facile method to synthesize …
efficient metal utilization and unique properties. Finding a green, facile method to synthesize …
Direct synthesis of a covalent triazine‐based framework from aromatic amides
There have been extensive efforts to synthesize crystalline covalent triazine‐based frameworks
(CTFs) for practical applications and to realize their potential. The phosphorus pentoxide …
(CTFs) for practical applications and to realize their potential. The phosphorus pentoxide …
[HTML][HTML] STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
SP Totten, YK Im, E Cepeda Cañedo, O Najyb… - Nature …, 2021 - nature.com
Bioenergetic perturbations driving neoplastic growth increase the production of reactive
oxygen species (ROS), requiring a compensatory increase in ROS scavengers to limit oxidative …
oxygen species (ROS), requiring a compensatory increase in ROS scavengers to limit oxidative …
[PDF][PDF] Translational and HIF-1α-dependent metabolic reprogramming underpin metabolic plasticity and responses to kinase inhibitors and biguanides
There is increasing interest in therapeutically exploiting metabolic differences between normal
and cancer cells. We show that kinase inhibitors (KIs) and biguanides synergistically and …
and cancer cells. We show that kinase inhibitors (KIs) and biguanides synergistically and …
[HTML][HTML] The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
…, N De Jay, MC Festa, YK Young, YK Im… - Nature …, 2017 - nature.com
Tyrosine kinase signalling within cancer cells is central to the establishment of an
immunosuppressive microenvironment. Although tyrosine kinase inhibitors act, in part, to augment …
immunosuppressive microenvironment. Although tyrosine kinase inhibitors act, in part, to augment …
[HTML][HTML] Vertical two-dimensional layered fused aromatic ladder structure
Planar two-dimensional (2D) layered materials such as graphene, metal-organic frameworks,
and covalent-organic frameworks are attracting enormous interest in the scientific …
and covalent-organic frameworks are attracting enormous interest in the scientific …
[PDF][PDF] Hydrophenazine-linked two-dimensional ladder-type crystalline fused aromatic network with high charge transport
Since the advent of graphene, the development of crystalline two-dimensional (2D) organic
materials with semiconducting features has been extensively explored for their potential …
materials with semiconducting features has been extensively explored for their potential …
Crystalline Porphyrazine‐Linked Fused Aromatic Networks with High Proton Conductivity
Fused aromatic networks (FANs) have been studied in efforts to overcome the low
physicochemical stability of metal–organic frameworks (MOFs) and covalent organic frameworks (…
physicochemical stability of metal–organic frameworks (MOFs) and covalent organic frameworks (…
Fused aromatic network with exceptionally high carrier mobility
Recently, studies of 2D organic layered materials with unique electronic properties have
generated considerable interest in the research community. However, the development of …
generated considerable interest in the research community. However, the development of …
Fused aromatic networks as a new class of gas hydrate inhibitors
Fused aromatic networks (FANs) are attracting considerable interest in the scientific community
because of their intriguing electronic properties and superior physiochemical stability …
because of their intriguing electronic properties and superior physiochemical stability …