Brainbow is a genetic cell-labeling technique where hundreds of different hues can be
generated by stochastic and combinatorial expression of a few spectrally distinct fluorescent …

The polarization of axon and dendrites underlies the ability of neurons to integrate and transmit
information in the brain. We show here that the serine/threonine kinase LKB1, previously …

Electrical activity in neurons is generally initiated in dendritic processes then propagated
along axons to synapses, where it is passed to other neurons. Major structural features of …

Advances in imaging and cell-labeling techniques have greatly enhanced our understanding
of developmental and neurobiological processes. Among vertebrates, zebrafish is uniquely …

A direct histological assay of axonal regeneration would have many advantages over
currently available behavioral, electrophysiological, and radiometric assays. We show that …

This protocol describes how to use the Brainbow strategy to label neurons in many different
hues. The Brainbow system uses a random Cre/lox recombination to create varied …

Current limitations in technology have prevented an extensive analysis of the connections
among neurons, particularly within nonmammalian organisms. We developed a transsynaptic …

How neurons connect to form functional circuits is central to the understanding of the
development and function of the nervous system. In the somatosensory system, perception of …

Extrinsic cues activate intrinsic signaling mechanisms to pattern neuronal shape and connectivity.
We showed previously that three cytoplasmic Ser/Thr kinases, LKB1, SAD-A, and SAD-…

Mammalian inner ear and fish lateral line sensory hair cells (HCs) detect fluid motion to
transduce environmental signals. Actively maintained ionic homeostasis of the mammalian inner …