User profiles for Y. Chhabra
Yash ChhabraFoxChase Cancer Center Verified email at fccc.edu Cited by 1170 |
Fibroblasts in cancer: Unity in heterogeneity
Y Chhabra, AT Weeraratna - Cell, 2023 - cell.com
Tumor cells do not exist in isolation in vivo, and carcinogenesis depends on the surrounding
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …
tumor microenvironment (TME), composed of a myriad of cell types and biophysical and …
Cardiovascular disease in patients with chronic kidney disease: a neglected subgroup
AK Subbiah, YK Chhabra, S Mahajan - Heart Asia, 2016 - heartasia.bmj.com
The burden of non-communicable diseases has increased exponentially over the past decade
and they account for majority of the health-related morbidity and mortality worldwide. In …
and they account for majority of the health-related morbidity and mortality worldwide. In …
Role of the growth hormone–IGF-1 axis in cancer
A substantial body of evidence supports a role for the growth hormone (GH)–IGF-1 axis in
cancer incidence and progression. This includes epidemiological evidence relating elevated …
cancer incidence and progression. This includes epidemiological evidence relating elevated …
Mechanism of activation of protein kinase JAK2 by the growth hormone receptor
Introduction Class I cytokines regulate key processes such as growth, lactation, hematopoiesis,
and immune function and contribute to oncogenesis. Although the extracellular domain …
and immune function and contribute to oncogenesis. Although the extracellular domain …
Stromal changes in the aged lung induce an emergence from melanoma dormancy
Disseminated cancer cells from primary tumours can seed in distal tissues, but may take several
years to form overt metastases, a phenomenon that is termed tumour dormancy. Despite …
years to form overt metastases, a phenomenon that is termed tumour dormancy. Despite …
[HTML][HTML] NFIB mediates BRN2 driven melanoma cell migration and invasion through regulation of EZH2 and MITF
While invasion and metastasis of tumour cells are the principle factor responsible for cancer
related deaths, the mechanisms governing the process remain poorly defined. Moreover, …
related deaths, the mechanisms governing the process remain poorly defined. Moreover, …
BRN 2, a POU erful driver of melanoma phenotype switching and metastasis
The POU domain family of transcription factors play a central role in embryogenesis and are
highly expressed in neural crest cells and the developing brain. BRN 2 is a class III POU …
highly expressed in neural crest cells and the developing brain. BRN 2 is a class III POU …
[HTML][HTML] A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation
Y Chhabra, HY Wong, LF Nikolajsen, H Steinocher… - Oncogene, 2018 - nature.com
Both humans and mice lacking functional growth hormone (GH) receptors are known to be
resistant to cancer. Further, autocrine GH has been reported to act as a cancer promoter. …
resistant to cancer. Further, autocrine GH has been reported to act as a cancer promoter. …
Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning
… Error bars indicate the standard deviations of enrichment scores calculated in Enrich2 (y-axis)
and standard deviation of final cell counts in the experiment from panel (B) (x-axis). ns, not …
and standard deviation of final cell counts in the experiment from panel (B) (x-axis). ns, not …
Deployment of distributed clustering approach in WSNs and IoTs
P Bhambri, Y Chhabra - Cloud and Fog Computing Platforms for …, 2022 - taylorfrancis.com
Wireless Sensor Networks are very useful technologies used in every department such as
military, health departments, education departments, agricultural departments, industrial …
military, health departments, education departments, agricultural departments, industrial …