Many nuclear proteins form lamin-dependent complexes, including LEM-domain proteins,
nesprins and SUN-domain proteins. These complexes have roles in chromatin organization, …

… elegans proteins (Lee et al. 2000), at least six Drosophila proteins, and in many human
proteins (Y. Gruenbaum, unpubl.). It will be of great interest to determine whether any of these …

Lamins are intermediate filament proteins that form a scaffold, termed nuclear lamina, at the
nuclear periphery. A small fraction of lamins also localize throughout the nucleoplasm. …

Hutchinson–Gilford progeria syndrome (HGPS) is a premature aging disorder, commonly
caused by a point mutation in the lamin A gene that results in a protein lacking 50 aa near the …

Although plant DNA has a high content of 5-methylcytosine (5mC 1 ) very little is known
about the distribution of this modification. Many of these methylations are found in the …

… In particular, specific MspI (CCGG) sites located in the 5"-flanking region of the human y-globin
genes are modified at the external cytosine. These unusual methyl moieties also seem to …

Caenorhabditis elegans has a single lamin gene, designated lmn-1 (previously termed
CeLam-1). Antibodies raised against the lmn-1 product (Ce-lamin) detected a 64-kDa nuclear …

… y axis, percent of nuclei in a given category (black column, class I; gray column, class II;
white column, class III). x axis, days (total number of nuclei scored). … Yosef Gruenbaum …

… Yosef GRUENBAUM*, Reuven STEIN, Howard CEDAR and Aharon RAZIN* … Herpes simplex
virus I DNA, h phage DNA and rabbit liver DNA were gifts from Y. Becker, G. Glaser and J. …

The novel SUN-domain family of nuclear envelope proteins interacts with various KASH-domain
partners to form SUN-domain-dependent'bridges' across the inner and outer nuclear …