[HTML][HTML] Partners in leaky gut syndrome: intestinal dysbiosis and autoimmunity

Y Kinashi, K Hase - Frontiers in immunology, 2021 - frontiersin.org
The intestinal surface is constitutively exposed to diverse antigens, such as food antigens,
food-borne pathogens, and commensal microbes. Intestinal epithelial cells have developed …

Experimental verification of beam characteristics for cyclotron-based epithermal neutron source (C-BENS)

…, K Fujita, G Kashino, Y Kinashi, Y Liu… - Applied Radiation and …, 2011 - Elsevier
A cyclotron-based epithermal neutron source has been developed for boron neutron capture
therapy. This system consists of a cyclotron accelerator producing 1.1-mA proton beams …

Characteristics comparison between a cyclotron-based neutron source and KUR-HWNIF for boron neutron capture therapy

…, Y Sakurai, M Suzuki, S Masunaga, Y Kinashi… - Nuclear Instruments and …, 2009 - Elsevier
At Kyoto University Research Reactor Institute (KURRI), 275 clinical trials of boron neutron
capture therapy (BNCT) have been performed as of March 2006, and the effectiveness of …

Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer

…, S Haginomori, Y Sakurai, Y Kinashi… - Journal of radiation …, 2014 - academic.oup.com
We retrospectively review outcomes of applying boron neutron capture therapy (BNCT) to
unresectable advanced or recurrent head and neck cancers. Patients who were treated with …

First attempt of boron neutron capture therapy (BNCT) for hepatocellular carcinoma

…, S Hagiwara, S Masunaga, Y Kinashi… - Japanese Journal of …, 2007 - academic.oup.com
A 60-year-old man with multiple hepatocellular carcinomas (HCCs) was enrolled as the first
patient in a pilot study for treating multiple liver tumors with boron neutron capture therapy (…

[HTML][HTML] Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis

…, M Hirota, Y Kinashi, H Oguchi, W Suda, Y Furusawa… - …, 2019 - thelancet.com
Background The dysbiosis of gut microbiota has been implicated in the pathogenesis of
inflammatory bowel diseases; however, the underlying mechanisms have not yet been …

The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice

K Ono, S Masunaga, M Suzuki, Y Kinashi… - International Journal of …, 1999 - Elsevier
Purpose: To increase the effect of boron neutron capture therapy (BNCT) on tumors in vivo,
the combined effects of para-boronophenylalanine (BPA) and borocaptate sodium (BSH) …

Radiobiological evidence suggesting heterogeneous microdistribution of boron compounds in tumors: its relation to quiescent cell population and tumor cure in …

K Ono, SI Masunaga, Y Kinashi… - … journal of radiation …, 1996 - europepmc.org
… Imamichi S, Chen L, Ito T, Tong Y, Onodera T, Sasaki Y, Nakamura S, Mauri P, Sanada Y,
Igaki H, Murakami Y, Suzuki M, Itami J, Masunaga S, Masutani M … Ono K, Masunaga S, Suzuki …

A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT)

…, H Kumada, H Kimura, S Masunaga, Y Kinashi… - Radiotherapy and …, 2008 - Elsevier
Two patients, one with malignant pleural mesothelioma and one with a malignant short
spindle cell tumor, received boron neutron capture therapy (BNCT). In each case, the tumors …

An alternative mechanism for radioprotection by dimethyl sulfoxide; possible facilitation of DNA double-strand break repair

…, M Suzuki, S Masunaga, Y Kinashi… - Journal of radiation …, 2010 - ieeexplore.ieee.org
The radioprotective effects of dimethyl sulfoxide (DMSO) have been known for many years,
and the suppression of hydroxyl (OH) radicals induced by ionizing radiation has been …