[HTML][HTML] Human blastoids model blastocyst development and implantation

…, G Sestini, M Novatchkova, Y Scholte op Reimer… - Nature, 2022 - nature.com
One week after fertilization, human embryos implant into the uterus. This event requires the
embryo to form a blastocyst consisting of a sphere encircling a cavity lodging the embryo …

Generating human blastoids modeling blastocyst-stage embryos and implantation

…, J Slovakova, M Novatchkova, Y Scholte op Reimer… - Nature protocols, 2023 - nature.com
… We also used the ROCK inhibitor Y-27632 to improve aggregation 58 and the STAT pathway
activator LIF that is used to maintain a blastocyst stage EPI-like state 33 and also improved …

A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression

EJ Vrij, YS Scholte op Reimer, LR Fuentes… - …, 2022 - journals.biologists.com
Embryogenesis is supported by dynamic loops of cellular interactions. Here, we create a
partial mouse embryo model to elucidate the principles of epiblast (Epi) and extra-embryonic …

Diversity of the insect pathogenic fungi in the genus Metarhizium in New Zealand

TR Glare, Y Scholte Op Reimer… - New Zealand Journal …, 2021 - Taylor & Francis
Invertebrate-pathogenic fungi in the genus Metarhizium are commonly found throughout the
world on a wide range of different arthropod hosts. Some strains have been developed as …

[PDF][PDF] Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero

…, H Kagawa, G Sestini, HH Khoei, YSO Reimer… - Cell stem cell, 2022 - cell.com
The embryo instructs the allocation of cell states to spatially regulate functions. In the
blastocyst, patterning of trophoblast (TR) cells ensures successful implantation and placental …

[HTML][HTML] Barriers and facilitators for shared decision making in older patients with multiple chronic conditions: a systematic review

…, MM Minkman, WJM Scholte Op Reimer - BMC geriatrics, 2021 - Springer
Background The aim of this study was to describe barriers and facilitators for shared
decision making (SDM) as experienced by older patients with multiple chronic conditions (MCCs), …

The prognostic value of heart rate recovery in patients with coronary artery disease: a systematic review and meta-analysis

…, J Limpens, H Jorstad, C Lucas, WS op Reimer… - American Heart …, 2018 - Elsevier
… Terbraak MSc b , Jacqueline Limpens PhD c , Harald Jorstad MD PhD a , Cees Lucas PhD
d , Wilma Scholte op Reimer RN, PhD b , S. Matthijs Boekholdt a , Gerben ter Riet MD PhD b …

Self-organization of post-implantation-like embryonic tissues from blastoids

EJ Vrij, Y Scholte op Reimer, J Frias Aldeguer… - BioRxiv, 2019 - biorxiv.org
The early mammalian conceptus (blastocyst) contains two supporting extraembryonic tissues
- the trophectoderm and the primitive endoderm (PrE) - that encase and guide the epiblast (…

[HTML][HTML] Barriers and facilitators with medication use during the transition from hospital to home: a qualitative study among patients

…, BM Buurman, WJM Scholte op Reimer… - BMC health services …, 2019 - Springer
… Daliri S, Hugtenburg JG, Ter Riet G, van den Bemt BJF, Buurman BM, Scholte Op Reimer
WJM, et al. The effect of a pharmacy-led transitional care … Wilma JM Scholte op Reimer

Stroke-associated infection is an independent risk factor for poor outcome after acute ischemic stroke: data from the Netherlands Stroke Survey

FH Vermeij, WJM Scholte op Reimer… - Cerebrovascular …, 2009 - karger.com
Background: Infections are a common and serious threat to patients with acute ischemic
stroke. The aim of this study was to assess the effect of infection on mortality and functional …