Human chromosome 14q32.2 carries a cluster of imprinted genes including paternally expressed
genes (PEGs) such as DLK1 and RTL1 and maternally expressed genes (MEGs) such …

Eutherian placenta, an organ that emerged in the course of mammalian evolution, provides
essential architecture, the so-called feto-maternal interface, for fetal development by …

Pancreatic cancer is a highly aggressive malignancy due to elevated mitotic activities and
epithelial-mesenchymal transition (EMT). Oncogenic RAS and transforming growth factor-β …

Undernutrition during pregnancy reduces birth weight and programmes adult phenotype
with consequences for life expectancy, but its effects on the phenotype of the placenta, …

Background: Clinical trials of probiotic treatment for Crohn’s disease (CD) have yielded
conflicting results. This study assessed the clinical usefulness of combined probiotic and …

Sox2 is a member of the high mobility group (HMG) domain DNA-binding proteins for
transcriptional control and chromatin architecture. The HMG domain of Sox2 binds the DNA to …

Background Vascular dementia (VaD) has been considered to be more prevalent than
Alzheimer disease in Japan. However, this might be the result of overdiagnosis stemming from …

We examined the relations between cognitive function and age and education in the normal
elderly population. As per the community‐based stroke, dementia, and bed confinement pre…

We investigated community-based data of the Mini-Mental State Examination (MMSE) scores
of elderly residents along with the effects of age and educational level. MMSE was planned …

Background Recent reports suggest that Helicobacter pylori infection can potentially increase
the risk of colorectal cancer. The purpose of this study was to assess the association …