The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds
90% when diagnosed after age 65. Most cases arise without any detectable early symptoms …

Study of the origin and development of cerebellar tumours has been hampered by the
complexity and heterogeneity of cerebellar cells that change over the course of development. …

Background We present the genome sequence of the tammar wallaby, Macropus eugenii,
which is a member of the kangaroo family and the first representative of the iconic hopping …

The SK-BR-3 cell line is one of the most important models for HER2+ breast cancers, which
affect one in five breast cancer patients. SK-BR-3 is known to be highly rearranged, although …

By utilizing an integrated cell-free DNA approach, liquid biopsy shows earlier detection of
cancer in patients with LFS compared with current clinical surveillance methods such as …

Schwannomatosis (SWNTS) is a genetic cancer predisposition syndrome that manifests as
multiple and often painful neuronal tumors called schwannomas (SWNs). While germline …

Balanced Translocations in Embryos Balanced chromosomal rearrangements are associated
with infertility and recurrent miscarriage but are difficult to detect. In this study, long-read …

Background Travel-related dissemination of SARS-CoV-2 continues to contribute to the
global pandemic. A novel SARS-CoV-2 lineage (B.1.177) reportedly arose in Spain in the …

A recurring historic finding in cancer drug development is encouraging antitumor effects
observed in tumor-bearing mice that fail to translate into the clinic. An intriguing exception to this …

The Canadian beaver (Castor canadensis) is the largest indigenous rodent in North America.
We report a draft annotated assembly of the beaver genome, the first for a large rodent and …