User profiles for Yadong Huang
 | Yadong Huang, MD, PhD.Senior Investigator, Gladstone Institute of Neurological Disease, Professor of Neurology … Verified email at gladstone.ucsf.edu Cited by 21994 |
[HTML][HTML] Alzheimer mechanisms and therapeutic strategies
There are still no effective treatments to prevent, halt, or reverse Alzheimer's disease, but
research advances over the past three decades could change this gloomy picture. Genetic …
research advances over the past three decades could change this gloomy picture. Genetic …
Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease
…, KH Weisgraber, Y Huang - Proceedings of the …, 2006 - National Acad Sciences
The premise of this review is that apolipoprotein (apo) E4 is much more than a contributing
factor to neurodegeneration. ApoE has critical functions in redistributing lipids among CNS …
factor to neurodegeneration. ApoE has critical functions in redistributing lipids among CNS …
High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse …
G Assmann, H Schulte, A von Eckardstein, Y Huang - Atherosclerosis, 1996 - Elsevier
The incidence of coronary heart disease (CHD) was assessed via the Prospective Cardiovascular
Münster (PROCAM) study in 19 698 volunteer subjects aged between 16 and 65 years…
Münster (PROCAM) study in 19 698 volunteer subjects aged between 16 and 65 years…
ApoE genotype accounts for the vast majority of AD risk and AD pathology
J Raber, Y Huang, JW Ashford - Neurobiology of aging, 2004 - Elsevier
In this review, evidence is provided that apolipoprotein E (apoE) genotype accounts for the
majority of Alzheimer’s disease (AD) risk and pathology. The three major human isoforms, …
majority of Alzheimer’s disease (AD) risk and pathology. The three major human isoforms, …
Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
… Author links open overlay panel Yadong Huang a b c d , Robert W. Mahley a b d e …
pathways (Huang, 2010, Huang and Mucke, 2012, Huang et al., 2004, Mahley and …
pathways (Huang, 2010, Huang and Mucke, 2012, Huang et al., 2004, Mahley and …
[HTML][HTML] Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS
Apolipoprotein (apo) E has roles beyond lipoprotein metabolism. The detrimental effects of
apoE4 in cardiovascular, neurological, and infectious diseases correlate with its structural …
apoE4 in cardiovascular, neurological, and infectious diseases correlate with its structural …
[PDF][PDF] Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor
…, G Li, D Walker, WR Zhang, AC Kreitzer, Y Huang - Cell stem cell, 2012 - cell.com
The generation of induced pluripotent stem cells (iPSCs) and induced neuronal cells (iNCs)
from somatic cells provides new avenues for basic research and potential transplantation …
from somatic cells provides new avenues for basic research and potential transplantation …
Overview on the recent study of antimicrobial peptides: origins, functions, relative mechanisms and application
Y Li, Q Xiang, Q Zhang, Y Huang, Z Su - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs), which are produced by several species including insects,
other animals, micro-organisms and synthesis, are a critical component of the natural defense …
other animals, micro-organisms and synthesis, are a critical component of the natural defense …
[HTML][HTML] Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): questions, quandaries, and paradoxes
Type III hyperlipoproteinemia (HLP) is a genetic disorder characterized by accumulation of
remnant lipoproteins in the plasma and development of premature atherosclerosis. Although …
remnant lipoproteins in the plasma and development of premature atherosclerosis. Although …
Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus
To study the profile and regulation of apolipoprotein E (apoE) expression in the CNS, we
generated mice in which apoE expression can be detected in vivo with unprecedented …
generated mice in which apoE expression can be detected in vivo with unprecedented …