User profiles for Yael Yaniv

Yael Yaniv

Associate Professor, Technion
Verified email at bm.technion.ac.il
Cited by 2923

Role of glycogen synthase kinase-3β in cardioprotection

M Juhaszova, DB Zorov, Y Yaniv, HB Nuss… - Circulation …, 2009 - Am Heart Assoc
Limitation of infarct size by ischemic/pharmacological pre- and postconditioning involves
activation of a complex set of cell-signaling pathways. Multiple lines of evidence implicate the …

Regulation and pharmacology of the mitochondrial permeability transition pore

DB Zorov, M Juhaszova, Y Yaniv, HB Nuss… - Cardiovascular …, 2009 - academic.oup.com
The ‘mitochondrial permeability transition', characterized by a sudden induced change of
the inner mitochondrial membrane permeability for water as well as for small substances (≤1.5 …

[HTML][HTML] From two competing oscillators to one coupled-clock pacemaker cell system

Y Yaniv, EG Lakatta, VA Maltsev - Frontiers in physiology, 2015 - frontiersin.org
At the beginning of this century, debates regarding “what are the main control mechanisms
that ignite the action potential (AP) in heart pacemaker cells” dominated the …

Synchronization of sinoatrial node pacemaker cell clocks and its autonomic modulation impart complexity to heart beating intervals

Y Yaniv, I Ahmet, J Liu, AE Lyashkov, TR Guiriba… - Heart Rhythm, 2014 - Elsevier
Background A reduction of complexity of heart beating interval variability that is associated
with an increased morbidity and mortality in cardiovascular disease states is thought to derive …

[HTML][HTML] Signatures of the autonomic nervous system and the heart's pacemaker cells in canine electrocardiograms and their applications to humans

…, I Weiser-Bitoun, GE Billman, Y Yaniv - Scientific Reports, 2020 - nature.com
Heart rate and heart rate variability (HRV) are mainly determined by the autonomic nervous
system (ANS), which interacts with receptors on the sinoatrial node (SAN; the heart’s primary …

[HTML][HTML] Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3

…, E Thomassen-Wolf, E Rom, R Adar, Y Yaniv… - Journal of Biological …, 2003 - ASBMB
The human combinatorial antibody library Fab 1 (HuCAL®-Fab 1) was generated by
transferring the heavy and light chain variable regions from the previously constructed single-chain …

[HTML][HTML] PhysioZoo: a novel open access platform for heart rate variability analysis of mammalian electrocardiographic data

…, A Alexandrovich, E Konyukhov, Y Yaniv - Frontiers in …, 2018 - frontiersin.org
Background: The time variation between consecutive heartbeats is commonly referred to as
heart rate variability (HRV). Loss of complexity in HRV has been documented in several …

ATP Synthase K+- and H+-Fluxes Drive ATP Synthesis and Enable Mitochondrial K+-“Uniporter” Function: I. Characterization of Ion Fluxes

…, E Kobrinsky, DB Zorov, HB Nuss, Y Yaniv… - Function, 2022 - academic.oup.com
ATP synthase (F 1 F o ) synthesizes daily our body's weight in ATP, whose production-rate
can be transiently increased several-fold to meet changes in energy utilization. Using purified …

Meeting the unmet needs of clinicians from AI systems showcased for cardiology with deep-learning–based ECG analysis

…, A Schuster, AM Bronstein, Y Yaniv - Proceedings of the …, 2021 - National Acad Sciences
Despite their great promise, artificial intelligence (AI) systems have yet to become ubiquitous
in the daily practice of medicine largely due to several crucial unmet needs of healthcare …

New evidence for coupled clock regulation of the normal automaticity of sinoatrial nodal pacemaker cells: Bradycardic effects of ivabradine are linked to suppression …

Y Yaniv, S Sirenko, BD Ziman, HA Spurgeon… - Journal of molecular and …, 2013 - Elsevier
Beneficial clinical bradycardic effects of ivabradine (IVA) have been interpreted solely on the
basis of I f inhibition, because IVA specifically inhibits I f in sinoatrial nodal pacemaker cells (…