Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection
MJ Davis, TM Tsang, Y Qiu, JK Dayrit, JB Freij… - MBio, 2013 - Am Soc Microbiol
The outcome of cryptococcal pneumonia correlates with local macrophage polarization status,
as M1 and M2 polarization marks protective and nonprotective responses, respectively. …
as M1 and M2 polarization marks protective and nonprotective responses, respectively. …
[HTML][HTML] Potential role of flavivirus NS2B-NS3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: a review
…, NJ Stevenson, MN Anwar, K Liu, J Wei, Y Qiu… - Viruses, 2021 - mdpi.com
Flaviviruses are known to cause a variety of diseases in humans in different parts of the
world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore …
world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore …
Cryptococcus neoformans–induced macrophage lysosome damage crucially contributes to fungal virulence
MJ Davis, AJ Eastman, Y Qiu, B Gregorka… - The Journal of …, 2015 - journals.aai.org
Upon ingestion by macrophages, Cryptococcus neoformans can survive and replicate
intracellularly unless the macrophages become classically activated. The mechanism enabling …
intracellularly unless the macrophages become classically activated. The mechanism enabling …
[HTML][HTML] Immune Modulation Mediated by Cryptococcal Laccase Promotes Pulmonary Growth and Brain Dissemination of Virulent Cryptococcus neoformans in Mice
Y Qiu, MJ Davis, JK Dayrit, Z Hadd, DL Meister… - 2012 - journals.plos.org
C. neoformans is a leading cause of fatal mycosis linked to CNS dissemination. Laccase,
encoded by the LAC1 gene, is an important virulence factor implicated in brain dissemination …
encoded by the LAC1 gene, is an important virulence factor implicated in brain dissemination …
[HTML][HTML] Genetic characterization of porcine reproductive and respiratory syndrome virus from Eastern China during 2017–2022
…, Y Yang, Q Xia, Z Guan, J Zhang, B Li, Y Qiu… - Frontiers in …, 2022 - frontiersin.org
Porcine reproductive and respiratory syndrome (PRRS) is an immunosuppressive disease
caused by PRSS virus (PRRSV). PRRSV mainly causes reproductive disorders in pregnant …
caused by PRSS virus (PRRSV). PRRSV mainly causes reproductive disorders in pregnant …
[HTML][HTML] Nitazoxanide inhibits the replication of Japanese encephalitis virus in cultured cells and in a mouse model
Z Shi, J Wei, X Deng, S Li, Y Qiu, D Shao, B Li, K Zhang… - Virology journal, 2014 - Springer
Background Japanese encephalitis virus (JEV) has a significant impact on public health. An
estimated three billion people in 'at-risk’ regions remain unvaccinated and the number of …
estimated three billion people in 'at-risk’ regions remain unvaccinated and the number of …
Antimicrobial Resistance of Campylobacter Species Isolated from Broilers in Live Bird Markets in Shanghai, China
…, H Jia, J Wei, D Shao, K Liu, Y Shi, Y Qiu… - Foodborne …, 2017 - liebertpub.com
This study was conducted to determine the prevalence of antimicrobial resistance in
Campylobacter spp. isolates from broilers in live bird markets (LBMs). A total of 209 Campylobacter …
Campylobacter spp. isolates from broilers in live bird markets (LBMs). A total of 209 Campylobacter …
[HTML][HTML] NS5-V372A and NS5-H386Y variations are responsible for differences in interferon α/β induction and co-contribute to the replication advantage of Japanese …
…, X Wang, Q Xia, X Ma, K Liu, B Li, D Shao, Y Qiu… - PLoS …, 2020 - journals.plos.org
Japanese encephalitis virus (JEV) genotype I (GI) replicates more efficiently than genotype
III (GIII) in birds, and this difference is considered to be one of the reasons for the JEV …
III (GIII) in birds, and this difference is considered to be one of the reasons for the JEV …
[HTML][HTML] The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities
X Deng, X Li, Y Shen, Y Qiu, Z Shi, D Shao, Y Jin… - Virology journal, 2010 - Springer
Background Marek's disease virus (MDV) is an oncogenic herpesvirus, which causes malignant
lymphoma in chickens. The Meq protein of MDV, which is expressed abundantly in MDV-…
lymphoma in chickens. The Meq protein of MDV, which is expressed abundantly in MDV-…
Cryptococcal heat shock protein 70 homolog Ssa1 contributes to pulmonary expansion of Cryptococcus neoformans during the afferent phase of the immune …
AJ Eastman, X He, Y Qiu, MJ Davis… - The Journal of …, 2015 - journals.aai.org
Numerous virulence factors expressed by Cryptococcus neoformans modulate host
defenses by promoting nonprotective Th2-biased adaptive immune responses. Prior studies …
defenses by promoting nonprotective Th2-biased adaptive immune responses. Prior studies …