[HTML][HTML] Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

…, Q Wu, P Tian, Y Wang, S Yang, C Liang, Y Liang… - Cancer cell, 2021 - cell.com
Lung metastasis is the major cause of breast cancer-related mortality. The neutrophil-associated
inflammatory microenvironment aids tumor cells in metastatic colonization in lungs. …

Secular trends in the prevalence of general and abdominal obesity among Chinese adults, 1993–2009

B Xi, Y Liang, T He, KH Reilly, Y Hu, Q Wang… - Obesity …, 2012 - Wiley Online Library
The objective of this study is to examine the trends in body mass index (BMI), waist circumference
(WC) and prevalence of overweight (BMI 25–27.49 kg m −2 ), general obesity (BMI ≥ …

[HTML][HTML] Tobacco use and second-hand smoke exposure in young adolescents aged 12–15 years: data from 68 low-income and middle-income countries

B Xi, Y Liang, Y Liu, Y Yan, M Zhao, C Ma… - The Lancet Global …, 2016 - thelancet.com
Background Tobacco use is an important risk factor for non-communicable diseases
worldwide. However, the global extent and prevalence of tobacco use in adolescents is poorly …

Childhood obesity affects adult metabolic syndrome and diabetes

Y Liang, D Hou, X Zhao, L Wang, Y Hu, J Liu, H Cheng… - Endocrine, 2015 - Springer
We seek to observe the association between childhood obesity by different measures and
adult obesity, metabolic syndrome (MetS), and diabetes. Thousand two hundred and nine …

Prevalence and trends in tobacco use among adolescents aged 13–15 years in 143 countries, 1999–2018: findings from the Global Youth Tobacco Surveys

C Ma, B Xi, Z Li, H Wu, M Zhao, Y Liang… - The Lancet Child & …, 2021 - thelancet.com
Background Tobacco use is a leading preventable cause of morbidity and mortality worldwide.
Little is known about recent prevalence and trends in tobacco use among adolescents …

[HTML][HTML] Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63

…, M Cong, T Wang, Y He, C Ma, P Tian, Y Liang… - Nature …, 2021 - nature.com
Disseminated tumor cells often fall into a long term of dormant stage, characterized by
decreased proliferation but sustained survival, in distant organs before awakening for metastatic …

[HTML][HTML] Global trends in the prevalence of secondhand smoke exposure among adolescents aged 12–16 years from 1999 to 2018: an analysis of repeated cross …

C Ma, EG Heiland, Z Li, M Zhao, Y Liang… - The Lancet Global …, 2021 - thelancet.com
Background Secondhand smoke exposure can cause morbidity and premature mortality.
However, the global prevalence of, and trends in, secondhand smoke exposure among …

[HTML][HTML] Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis

Y Liang, H Wu, R Lei, RA Chong, Y Wei, X Lu… - Journal of Biological …, 2012 - ASBMB
The application of functional genomic analysis of breast cancer metastasis has led to the
identification of a growing number of organ-specific metastasis genes, which often function in …

SCUBE2 mediates bone metastasis of luminal breast cancer by modulating immune-suppressive osteoblastic niches

…, Z Jia, Y He, W Luo, X Lv, Y Wang, P Zhang, Y Liang… - Cell Research, 2023 - nature.com
Estrogen receptor (ER)-positive luminal breast cancer is a subtype with generally lower risk
of metastasis to most distant organs. However, bone recurrence occurs preferentially in …

[HTML][HTML] IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer

…, X Zhang, Y Xiao, P Zhang, Y Liang… - The Journal of …, 2022 - Am Soc Clin Investig
Bone is a common site of metastasis in lung cancer, but the regulatory mechanism remains
incompletely understood. Osteoclasts are known to play crucial roles in osteolytic bone …