User profiles for Yan Yi Chen

YICHEN YAN

University of California, Los Angeles
Verified email at g.ucla.edu
Cited by 607

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

…, TL Roth, DN Nguyen, WG Pfeifer, YY Chen… - Nature …, 2023 - nature.com
Enhancing CRISPR-mediated site-specific transgene insertion efficiency by homology-directed
repair (HDR) using high concentrations of double-stranded DNA (dsDNA) with Cas9 …

[PDF][PDF] Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response

…, K Sun, C Wang, L Chen, X Xiao, X Zheng, S Chen… - Cell host & …, 2021 - cell.com
The SARS-CoV-2 virus, the causative agent of COVID-19, is undergoing constant mutation.
Here, we utilized an integrative approach combining epidemiology, virus genome …

[HTML][HTML] RASA2 ablation in T cells boosts antigen sensitivity and long-term function

…, E Shifrut, N Kale, WA Nyberg, F Blaeschke, YY Chen… - Nature, 2022 - nature.com
The efficacy of adoptive T cell therapies for cancer treatment can be limited by suppressive
signals from both extrinsic factors and intrinsic inhibitory checkpoints 1 , 2 . Targeted gene …

Superhydrophobic photothermal icephobic surfaces based on candle soot

…, Y Du, Y Alsaid, D Wu, M Hua, Y Yan… - Proceedings of the …, 2020 - National Acad Sciences
Ice accumulation causes various problems in our daily life for human society. The daunting
challenges in ice prevention and removal call for novel efficient antiicing strategies. Recently, …

Comparing machine learning algorithms in predicting thermal sensation using ASHRAE Comfort Database II

M Luo, J Xie, Y Yan, Z Ke, P Yu, Z Wang, J Zhang - Energy and Buildings, 2020 - Elsevier
Predicting building occupants’ thermal comfort via machine learning (ML) is a hot research
topic. Many algorithms and data processing methods have been applied to predict thermal …

Genome Sequence of the Milbemycin-Producing Bacterium Streptomycesbingchenggensis

…, J An, JJ Wang, J Tian, L Jiang, YH Chen… - Journal of …, 2010 - Am Soc Microbiol
Streptomyces bingchenggensis is a soil-dwelling bacterium producing the commercially
important anthelmintic macrolide milbemycins. Besides milbemycins, the insecticidal polyether …

Enhancement on cycle performance of Zn anodes by activated carbon modification for neutral rechargeable zinc ion batteries

H Li, C Xu, C Han, Y Chen, C Wei, B Li… - Journal of the …, 2015 - iopscience.iop.org
A novel composite anode is prepared by mixing zinc particles with activated carbon (AC) to
improve the cycle performance of the neutral rechargeable zinc ion batteries. Galvanostatic …

[HTML][HTML] A universal artificial intelligence platform for collaborative management of cataracts

…, K Chen, T Yu, D Wu, C Li, Y Chen, M Zou, C Chen… - The Lancet, 2019 - thelancet.com
Background Common diseases are not satisfactorily managed under the current health-care
system because of inadequate medical resources and limited accessibility. We aimed to …

Tunable sponge‐like hierarchically porous hydrogels with simultaneously enhanced diffusivity and mechanical properties

…, R Khodambashi, R Rico, M Hua, Y Yan… - Advanced …, 2021 - Wiley Online Library
Crosslinked polymers and gels are important in soft robotics, solar vapor generation, energy
storage, drug delivery, catalysis, and biosensing. However, their attractive mass transport …

[HTML][HTML] Flexible asymmetric supercapacitors based on ultrathin two-dimensional nanosheets with outstanding electrochemical performance and aesthetic property

S Shi, C Xu, C Yang, Y Chen, J Liu, F Kang - Scientific reports, 2013 - nature.com
Flexible asymmetric supercapacitors with excellent electrochemical performance and
aesthetic property are realized by using ultrathin two-dimensional (2D) MnO 2 and graphene …