User profiles for Yan Zhen

Zhen Yan

- Verified email at vtc.vt.edu - Cited by 27515

Zhen Yan

- Verified email at buffalo.edu - Cited by 20828

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

M Popoli, Z Yan, BS McEwen… - Nature Reviews …, 2012 - nature.com
Mounting evidence suggests that acute and chronic stress, especially the stress-induced
release of glucocorticoids, induces changes in glutamate neurotransmission in the prefrontal …

Coordinated expression of dopamine receptors in neostriatal medium spiny neurons

DJ Surmeier, WJ Song, Z Yan - Journal of neuroscience, 1996 - Soc Neuroscience
In recent years, the distribution of dopamine receptor subtypes among the principal neurons
of the neostriatum has been the subject of debate. Conventional anatomical and …

[HTML][HTML] Exercise stimulates Pgc-1α transcription in skeletal muscle through activation of the p38 MAPK pathway

…, C Gumbs, PB Rosenberg, RS Williams, Z Yan - Journal of Biological …, 2005 - ASBMB
Peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) promotes mitochondrial
biogenesis and slow fiber formation in skeletal muscle. We hypothesized that activation of …

[HTML][HTML] A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

…, IR Lanza, KA Rasbach, M Okutsu, KS Nair, Z Yan… - Cell, 2012 - cell.com
PGC-1α is a transcriptional coactivator induced by exercise that gives muscle many of the
best known adaptations to endurance-type exercise but has no effects on muscle strength or …

[HTML][HTML] Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1α muscle-specific knock-out animals

…, F Liu, E Maratos-Flier, NK LeBrasseur, Z Yan… - Journal of Biological …, 2007 - ASBMB
The transcriptional coactivator peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α)
is a key integrator of neuromuscular activity in skeletal muscle. Ectopic expression of …

Improved methods for predicting peptide binding affinity to MHC class II molecules

…, P Marcatili, S Buus, JA Greenbaum, Z Yan… - …, 2018 - Wiley Online Library
Major histocompatibility complex class II ( MHC ‐ II ) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, …

Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity

LL Zhang, D Yan Liu, LQ Ma, ZD Luo, TB Cao… - Circulation …, 2007 - Am Heart Assoc
We tested the hypothesis that activation of transient receptor potential vanilloid type-1 (TRPV1)
by capsaicin prevents adipogenesis. TRPV1 channels in 3T3-L1-preadipocytes and …

microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7

JF Chen, Y Tao, J Li, Z Deng, Z Yan, X Xiao… - Journal of Cell …, 2010 - rupress.org
Skeletal muscle satellite cells are adult stem cells responsible for postnatal skeletal muscle
growth and regeneration. Paired-box transcription factor Pax7 plays a central role in satellite …

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

JA Bibb, GL Snyder, A Nishi, Z Yan, L Meijer… - Nature, 1999 - nature.com
The physiological state of the cell is controlled by signal transduction mechanisms which
regulate the balance between protein kinase and protein phosphatase activities 1 . Here we …

[PDF][PDF] Repeated stress causes cognitive impairment by suppressing glutamate receptor expression and function in prefrontal cortex

EY Yuen, J Wei, W Liu, P Zhong, X Li, Z Yan - Neuron, 2012 - cell.com
Chronic stress could trigger maladaptive changes associated with stress-related mental
disorders; however, the underlying mechanisms remain elusive. In this study, we found that …