The host immune response to bone biomaterials is vital in determining scaffold fates and
bone regeneration outcomes. The nanometer-scale interface of biomaterials, which …

Background Osteoarthritis (OA) is an important subtype of temporomandibular disorders. A
simple and reproducible animal model that mimics the histopathologic changes, both in the …

SARS-CoV-2 infection-induced hyper-inflammation links to the acute lung injury and COVID-19
severity. Identifying the primary mediators that initiate the uncontrolled hypercytokinemia …

Organ development requires complex signaling by cells in different tissues. Epithelium and
mesenchyme interactions are crucial for the development of skin, hair follicles, kidney, lungs, …

Nanoscale replication of the hierarchical organization of minerals in biogenic mineralized
tissues is believed to contribute to the better mechanical properties of biomimetic collagen …

Objectives Mechanical force plays an important role in modulating stem cell fate and behaviours.
However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus …

Periodontal ligament stem cells (PDLSCs) possess self-renewal, multilineage differentiation,
and immunomodulatory properties. They play a crucial role in maintaining periodontal …

Objective To estimate the prevalence of HIV, HCV, HBV and co-infection with 2 or 3 viruses
and evaluate risk factors among injecting drug users (IDUs) in Yunnan province, China. …

Exosomes play a critical role in intracellular communication. The biogenesis and function of
exosomes are regulated by multiple biochemical factors. In the present study, we find that …

Extracellular vesicles (EVs) are heterogeneous nanoparticles actively released by cells that
comprise highly conserved and efficient systems of intercellular communication. In recent …