Objectives: The objective of this systematic review was to assess the analgesic efficacy of
duloxetine (DLX) for fibromyalgia (FM) and find out which dosage between 60 mg/d DLX and …

Purpose: To explore the potential mechanisms of glutamate and its receptors in stress-induced
hyperalgesia. Materials and methods: The stress-induced hyperalgesia, glutamate and …

Injury or disease in the somatosensory nervous system may cause broad molecular changes
and lead to neuropathic pain. Excitatory synaptic transmission in somatosensory pathways …

Management of chronic pain is still hard, and new analgesic drugs are needed. Evodiamine
(Evo) and rutaecarpine (Rut) are two major active components of Evodia rutaecarpa, a …

The retrosplenial cortex (RSC) is a vital area for storing remote memory and has recently
been found to undergo broad changes after peripheral nerve injury. However, little is known …

Exposure to chronic stress can influence nociception and further induce hyperalgesia. Whether
stress modulation of pain in female animals occurs in an estrous cycle-specific manner is …

The deficit of fragile X messenger ribonucleoprotein (FMRP) leads to intellectual disability in
human and animal models. Recently, it was shown that the protein arginine …

Exposure to stress could facilitate or inhibit pain responses (stress-induced hyperalgesia or
hypoalgesia, respectively). Fluoxetine is a selective serotonin (5-HT) reuptake inhibitor …

Deficits in fragile X mental retardation 1 protein lead to fragile X syndrome (FXS) with mental
retardation and social activity disorder. Until now, the neuronal circuits that mediate the …

Purpose The causes of anemia and the common side effects of cancer are multifactorial.
Malnutrition is one of the alleged components of the aforementioned complications. This study …