Background This article provides an overview of the first BioASQ challenge, a competition on
large-scale biomedical semantic indexing and question answering (QA), which took place …

This article provides an overview of BIOASQ, a new competition on biomedical semantic
indexing and question answering (QA). BIOASQ aims to push towards systems that will allow …

Chargaff' s second parity rule (PR2) states that complementary nucleotides are met with
almost equal frequencies in single stranded DNA. This is indeed the case for all bacterial and …

Deviations from Chargaff's 2nd parity rule, according to which A∼T and G∼C in single stranded
DNA, have been associated with replication as well as with transcription in prokaryotes. …

Background The deviation of the observed frequency of a word w from its expected frequency
in a given sequence x is used to determine whether or not the word is avoided. This …

Conserved, ultraconserved and other classes of constrained elements (collectively referred
as CNEs here), identified by comparative genomics in a wide variety of genomes, are non-…

Spatial distribution and clustering of repetitive elements are extensively studied during the
last years, as well as their colocalization with other genomic components. Here we investigate …

Scarce work has been done in the analysis of the composition of conserved non-coding
elements (CNEs) that are identified by comparisons of two or more genomes and are found to …

We study the size distribution of purine and pyrimidine clusters in coding and non-coding
DNA sequences. We observe that the cluster-size distribution P(s) follows an exponential …

Repetitive DNA sequences derived from transposable elements (TE) are distributed in a non-random
way, co-clustering with other classes of repeat elements, genes and other genomic …