TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

…, L Fasching, TS Macfarlan, Y Tarabay… - Genome …, 2013 - genome.cshlp.org
TRIM28 is critical for the silencing of endogenous retroviruses (ERVs) in embryonic stem (ES)
cells. Here, we reveal that an essential impact of this process is the protection of cellular …

Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4

…, C Brun, AB Juarez-Martinez, Y Tarabay… - Life science …, 2018 - life-science-alliance.org
Programmed formation of DNA double-strand breaks (DSBs) initiates the meiotic homologous
recombination pathway. This pathway is essential for proper chromosome segregation at …

The mammalian-specific Tex19. 1 gene plays an essential role in spermatogenesis and placenta-supported development

Y Tarabay, E Kieffer, M Teletin, C Celebi… - Human …, 2013 - academic.oup.com
STUDY QUESTION What is the consequence of Tex19.1 gene deletion in mice?
SUMMARY ANSWER The Tex19.1 gene is important in spermatogenesis and placenta-supported …

The role of epigenetics in addiction: clinical overview and recent updates

A Beayno, S El Hayek, P Noufi, Y Tarabay… - … Disorders: Methods and …, 2019 - Springer
Addiction is an international public health problem. It is a polygenic disorder best understood
by accounting for the interplay between genetic and environmental factors. A recent way of …

Tex19 paralogs are new members of the piRNA pathway controlling retrotransposon suppression

Y Tarabay, M Achour, M Teletin, T Ye… - Journal of Cell …, 2017 - journals.biologists.com
Tex19 genes are mammalian specific and duplicated to give Tex19.1 and Tex19.2 in some
species, such as the mouse and rat. It has been demonstrated that mutant Tex19.1 males …

[HTML][HTML] Tex19 and Sectm1 concordant molecular phylogenies support co-evolution of both eutherian-specific genes

L Bianchetti, Y Tarabay, O Lecompte, R Stote… - BMC evolutionary …, 2015 - Springer
Background Transposable elements (TE) have attracted much attention since they shape
the genome and contribute to species evolution. Organisms have evolved mechanisms to …

Human genetics of male infertility

E Elinati - 2012 - theses.hal.science
Yara Tarabay: I couldn’t imagine the lab without you. Thank you for being here each time I
… I am indebted to Anastasia Salloum, Andre Eid, Maher El Mashriki, Ranine Tarabay, Mona …

[PDF][PDF] TITRE de la thèse

E ELINATI - theses.hal.science
Yara Tarabay: I couldn’t imagine the lab without you. Thank you for being here each time I
… I am indebted to Anastasia Salloum, Andre Eid, Maher El Mashriki, Ranine Tarabay, Mona …

Genetics of male infertility: genes implicated in non-obstructive azoospermia and severe oligozoospermia

Ö Okutman - 2015 - theses.hal.science
Among couples with a desire for a child, male factor is responsible approximately 20%.
Despite long years of assisted reproductive activities, a significant number of cases remain …

[BOOK][B] Psychiatric Disorders

FH Kobeissy - 2019 - Springer
As the of field neuroscience is evolving, newly discoveries at the cellular and molecular levels
are revolutionizing the previous classical concepts into new developed understandings, …