[HTML][HTML] Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity
Anti-tumour inflammatory cytokines are highly toxic when administered systemically. Here,
in multiple syngeneic mouse models, we show that the intratumoural injection of …
in multiple syngeneic mouse models, we show that the intratumoural injection of …
[HTML][HTML] Engineered immunogen binding to alum adjuvant enhances humoral immunity
Adjuvants are central to the efficacy of subunit vaccines. Aluminum hydroxide (alum) is the
most commonly used vaccine adjuvant, yet its adjuvanticity is often weak and mechanisms of …
most commonly used vaccine adjuvant, yet its adjuvanticity is often weak and mechanisms of …
Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies
Effective antitumor immunity in mice requires activation of the type I interferon (IFN) response
pathway. IFNα and IFNβ therapies have proven promising in humans, but suffer from …
pathway. IFNα and IFNβ therapies have proven promising in humans, but suffer from …
Dopamine, immunity, and disease
…, SM Matt, EA Nickoloff-Bybel, V Pappa, Y Agarwal… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …
regulating many processes including reward, movement, and cognition. Dopamine also …
[HTML][HTML] The BLT Humanized Mouse Model as a Tool for Studying Human Gamma Delta T Cell-HIV Interactions In Vivo
Gamma-delta (γδ) T cells recognize antigens in a major histocompatibility complex (MHC)
independent and have cytotoxic capability. Human immunodeficiency virus (HIV) infection …
independent and have cytotoxic capability. Human immunodeficiency virus (HIV) infection …
Osseointegration of machined, injection moulded and oxygen plasma modified PEEK implants in a sheep model
Machined and injection moulded polyetheretherketone (PEEK) implants with and without an
oxygen plasma modification were prepared and implanted in sheep cancellous and cortical …
oxygen plasma modification were prepared and implanted in sheep cancellous and cortical …
Enabling hand gesture customization on wrist-worn devices
…, C Brum, L Liang, B Suh, SK Gupta, Y Agarwal… - Proceedings of the …, 2022 - dl.acm.org
We present a framework for gesture customization requiring minimal examples from users,
all without degrading the performance of existing gesture sets. To achieve this, we first …
all without degrading the performance of existing gesture sets. To achieve this, we first …
[HTML][HTML] Smart vehicle monitoring and assistance using cloud computing in vehicular Ad Hoc networks
The increasing number of on road vehicles has become a major cause for congestion,
accidents and pollution. Intelligent Transportation Systems (ITS) might be the key to achieve …
accidents and pollution. Intelligent Transportation Systems (ITS) might be the key to achieve …
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains
The immunostimulatory intracellular domains (ICDs) of chimaeric antigen receptors (CARs)
are essential for converting antigen recognition into antitumoural function. Although there are …
are essential for converting antigen recognition into antitumoural function. Although there are …
IoT based smart parking system
Y Agarwal, P Ratnani, U Shah… - 2021 5th international …, 2021 - ieeexplore.ieee.org
This paper discusses problems faced with traditional parking lots. It also lists the impact and
inconvenience caused because of inefficiency in traditional parking spaces. In this paper, …
inconvenience caused because of inefficiency in traditional parking spaces. In this paper, …