Background The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March,
2021. It has since rapidly become the predominant lineage, owing to high transmissibility. …

Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …

Background The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in
England. We aimed to investigate whether increases in the proportion of infections with this …

The replication of poliovirus, a positive-stranded RNA virus, requires translation of the
infecting genome followed by virus-encoded VPg and 3D polymerase-primed synthesis of a …

Unlike other positive‐stranded RNA viruses that use either a 5′‐cap structure or an internal
ribosome entry site to direct translation of their messenger RNA, calicivirus translation is …

Small RNA viruses have evolved many mechanisms to increase the capacity of their short
genomes. Here we describe the identification and characterization of a novel open reading …

Monitoring the spread of SARS-CoV-2 and reconstructing transmission chains has become
a major public health focus for many governments around the world. The modest mutation …

Two classes of viruses, namely members of the Potyviridae and Caliciviridae, use a novel
mechanism for the initiation of protein synthesis that involves the interaction of translation …

The mechanism and role of RNA structure elements in the replication and translation of
Caliciviridae remains poorly understood. Several algorithmically independent methods were …

Enteroviruses comprise a large group of mammalian pathogens that includes poliovirus.
Pathology in humans ranges from sub-clinical to acute flaccid paralysis, myocarditis and …