Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity

…, D Schooneman, T O'Toole, MR Mizee, Y Habani… - Nature, 2014 - nature.com
The impact of nutritional status during fetal life on the overall health of adults has been
recognized 1 ; however, dietary effects on the developing immune system are largely unknown. …

[HTML][HTML] VASP, zyxin and TES are tension-dependent members of Focal Adherens Junctions independent of the α-catenin-vinculin module

…, G Van Der Krogt, F Twiss, A Bongaarts, Y Habani… - Scientific reports, 2015 - nature.com
Mechanical forces are integrated at cadherin-based adhesion complexes to regulate
morphology and strength of cell-cell junctions and organization of associated F-actin. A central …

[HTML][HTML] The role of heparan sulfate and neuropilin 2 in VEGFA signaling in human endothelial tip cells and non-tip cells during angiogenesis in vitro

MG Dallinga, YI Habani, AWM Schimmel… - Cells, 2021 - mdpi.com
During angiogenesis, vascular endothelial growth factor A (VEGFA) regulates endothelial
cell (EC) survival, tip cell formation, and stalk cell proliferation via VEGF receptor 2 (VEGFR2). …

[HTML][HTML] IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis

MG Dallinga, YI Habani, RP Kayser… - Molecular Biology …, 2020 - Springer
Purpose We have previously identified insulin-like growth factor 2 (IGF2) and insulin-like
growth factor 1 receptor (IGF1R) as essential proteins for tip cell maintenance and sprouting …

[HTML][HTML] Differential roles of eNOS in late effects of VEGF-A on hyperpermeability in different types of endothelial cells

EK Bosma, S Darwesh, YI Habani, M Cammeraat… - Scientific reports, 2023 - nature.com
Vascular endothelial growth factor (VEGF)-A induces endothelial hyperpermeability, but the
molecular pathways remain incompletely understood. Endothelial nitric oxide synthase (…

[HTML][HTML] TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx

J Broertjes, J Klarenbeek, Y Habani, M Langeslag… - PLoS …, 2019 - journals.plos.org
The nonspecific divalent cation channel TRPM7 (transient receptor potential-melastatin-like
7) is involved in many Ca 2+ and Mg 2+ -dependent cellular processes, including survival, …

[HTML][HTML] Mirna levels as a biomarker for anti-vegf response in patients with diabetic macular edema

MJC Vader, YI Habani, RO Schlingemann… - Journal of personalized …, 2021 - mdpi.com
Background: The aim of this study was to investigate whether miRNA levels in the circulation
could serve as a predictive biomarker for responsiveness to anti-vascular endothelial …

[HTML][HTML] Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy

B Yetkin-Arik, AW Kastelein, I Klaassen… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Angiogenesis is required in cancer, including gynecological cancers, for the growth of
primary tumors and secondary metastases. Development of anti-angiogenesis therapy in …

[PDF][PDF] BBA-Reviews on Cancer

B Yetkin-Arik, AW Kastelein, I Klaassen, CHJR Jansen… - serval.unil.ch
Angiogenesis is required in cancer, including gynecological cancers, for the growth of
primary tumors and secondary metastases. Development of anti-angiogenesis therapy in …

[HTML][HTML] Matrix stiffness modulates tip cell formation through the p-PXN-Rac1-YAP signaling axis

Y Guo, F Mei, Y Huang, S Ma, Y Wei, X Zhang, M Xu… - Bioactive materials, 2022 - Elsevier
Endothelial tip cell outgrowth of blood-vessel sprouts marks the initiation of angiogenesis
which is critical in physiological and pathophysiological procedures. However, how …