Tuberculosis remains a fatal disease caused by Mycobacterium tuberculosis, which
contains various unique components that affect the host immune system. Trehalose-6,6′-…

Lipomannan (LM) and lipoarabinomannan (LAM) are mycobacterial glycolipids containing a
long mannose polymer. While they are implicated in immune modulations, the significance …

Phosphatidylinositol mannosides (PIMs) are a major class of glycolipids in all mycobacteria.
AcPIM2, a dimannosyl PIM, is both an end product and a precursor for polar PIMs, such as …

African trypanosomes, the cause of sleeping sickness, need massive amounts of myristate
to remodel glycosyl phosphatidylinositol (GPI) anchors on their surface glycoproteins. …

10.7554/eLife.37243.001 Rod-shaped mycobacteria expand from their poles, yet d-amino
acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We …

Phosphatidyl-inositol mannosides (PIM) are glycolipids unique to mycobacteria and other
related bacteria that stimulate host immune responses and are implicated in mycobacteria …

The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis , Mycobacterium leprae , and Mycobacterium avium . …

The plasma membrane of Mycobacterium sp. is the site of synthesis of several distinct classes
of lipids that are either retained in the membrane or exported to the overlying cell envelope…

Protected from host immune attack and antibiotic penetration by their unique cell envelope,
mycobacterial pathogens cause devastating human diseases such as tuberculosis. …

Mycobacteria have a distinctive glycolipid-rich outer membrane, the mycomembrane, which
is a critical target for tuberculosis drug development. However, proteins that associate with …