User profiles for Yasuhiro Yoshimura

Yasuhiro Yoshimura

Kyushu University
Verified email at m.kyushu-u.ac.jp
Cited by 190

[HTML][HTML] Human induced pluripotent stem cell–derived podocytes mature into vascularized glomeruli upon experimental transplantation

…, A Taguchi, Y Kaku, Y Yoshimura… - Journal of the …, 2016 - journals.lww.com
Glomerular podocytes express proteins, such as nephrin, that constitute the slit diaphragm,
thereby contributing to the filtration process in the kidney. Glomerular development has been …

[PDF][PDF] Human pluripotent stem cell-derived kidney organoids with improved collecting duct maturation and injury modeling

K Uchimura, H Wu, Y Yoshimura, BD Humphreys - Cell reports, 2020 - cell.com
Maximizing the potential of human kidney organoids for drug testing and regenerative medicine
and to model development and disease requires addressing cell immaturity, the lack of …

[PDF][PDF] Organoids from nephrotic disease-derived iPSCs identify impaired NEPHRIN localization and slit diaphragm formation in kidney podocytes

…, M Islam, S Sharmin, H Naganuma, Y Yoshimura… - Stem cell reports, 2018 - cell.com
Mutations in the NPHS1 gene, which encodes NEPHRIN, cause congenital nephrotic syndrome,
resulting from impaired slit diaphragm (SD) formation in glomerular podocytes. However…

A single-cell multiomic analysis of kidney organoid differentiation

Y Yoshimura, Y Muto, N Ledru, H Wu… - Proceedings of the …, 2023 - National Acad Sciences
Kidney organoids differentiated from pluripotent stem cells are powerful models of kidney
development and disease but are characterized by cell immaturity and off-target cell fates. …

[HTML][HTML] Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

Y Muto, EE Dixon, Y Yoshimura, H Wu… - Nature …, 2022 - nature.com
Autosomal dominant polycystic kidney disease (ADPKD) is the leading genetic cause of
end stage renal disease characterized by progressive expansion of kidney cysts. To better …

Manipulation of nephron-patterning signals enables selective induction of podocytes from human pluripotent stem cells

Y Yoshimura, A Taguchi, S Tanigawa… - Journal of the …, 2019 - journals.lww.com
Background Previous research has elucidated the signals required to induce nephron
progenitor cells (NPCs) from pluripotent stem cells (PSCs), enabling the generation of kidney …

Space solar power satellite for the Moon and Mars mission

A Baraskar, Y Yoshimura, S Nagasaki… - Journal of Space Safety …, 2022 - Elsevier
This paper presents an overview of space solar power satellites for the Moon and Mars
mission and simultaneously demonstrates the compression of traditional power generation …

[HTML][HTML] Ephedrine, dopamine, or doubtamine to treat hypotension with propofol during epidural anesthesia

T Kasaba, M Yamaga, T Iwasaki, Y Yoshimura… - Canadian journal of …, 2000 - Springer
Purpose: To compare the efficacy of ephedrine, dopamine and dobutamine for circulatory
support during thoracic epidural anesthesia after anesthetic induction with propofol. Methods: …

Elucidating the Proximal Tubule HNF4A Gene Regulatory Network in Human Kidney Organoids

Y Yoshimura, Y Muto, K Omachi, JH Miner… - Journal of the …, 2023 - journals.lww.com
Background The proximal tubule plays a major role in electrolyte homeostasis. Previous
studies have shown that HNF4A regulates reabsorption-related genes and promotes proximal …

Distribution of photoperiod-insensitive allele Ppd-A1a and its effect on heading time in Japanese wheat cultivars

…, M Chono, T Nishimura, M Sato, Y Yoshimura… - Breeding …, 2013 - jstage.jst.go.jp
The Ppd-A1 genotype of 240 Japanese wheat cultivars and 40 foreign cultivars was determined
using a PCR-based method. Among Japanese cultivars, only 12 cultivars, all of which …