Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics.
A simulation study demonstrated that attempts to categorize patients with a complex …

… Address correspondence to Yasutaka Kuniyoshi, MD, PhD, Department of Pediatrics,
Tsugaruhoken Medical COOP Kensei Hospital, 2-2-2 Ougi-machi, Hirosaki, 036-8511, Japan …

Background Neonatal jaundice and phototherapy have been associated with the
development of allergic diseases. It has been suggested, however, that effect estimates of the …

Background Most cases of beta-lactam allergy in children are likely to be mislabeled. This
study aimed to assess the prevalence of true positives, as determined by drug challenge tests, …

Background: The association between eczema and mental health problems in schoolchildren
has been underexplored. We aimed to investigate this association with the validated …

Fractures represent a major cause of disability in the elderly, and patients with fractures exhibit
a higher mortality rate than those without. Fractures are also an important health problem …

Keywords: area under curve; egg allergy; logistic regression; machine learning; nested
cross-validation; oral food challenge; predictive model; support vector machine EN area under …

Background Few studies have investigated the regional variations in the development of
neonatal hyperbilirubinemia. This study aimed to investigate regional variations in medical …

Background Serious isolated laryngeal injuries are uncommon in children. Case Report We
describe the case of an 8-year-old boy with laryngeal injury and pneumomediastinum due to …

We constructed an optimal machine learning (ML) method for predicting intravenous
immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD) using commonly …