[HTML][HTML] The pathomechanism, antioxidant biomarkers, and treatment of oxidative stress-related eye diseases

YJ Hsueh, YN Chen, YT Tsao, CM Cheng… - International Journal of …, 2022 - mdpi.com
Oxidative stress is an important pathomechanism found in numerous ocular degenerative
diseases. To provide a better understanding of the mechanism and treatment of oxidant/…

[HTML][HTML] Evaluating the effect of topical atropine use for myopia control on intraocular pressure by using machine learning

TE Wu, HA Chen, MJ Jhou, YN Chen… - Journal of Clinical …, 2020 - mdpi.com
Atropine is a common treatment used in children with myopia. However, it probably affects
intraocular pressure (IOP) under some conditions. Our research aims to analyze clinical data …

In vivo visualization of nitrate dynamics using a genetically encoded fluorescent biosensor

YN Chen, HN Cartwright, CH Ho - Science Advances, 2022 - science.org
Nitrate (NO 3 − ) uptake and distribution are critical to plant life. Although the upstream
regulation of NO 3 − uptake and downstream responses to NO 3 − in a variety of cells have been …

[HTML][HTML] Feedback inhibition of AMT1 NH4+-transporters mediated by CIPK15 kinase

HY Chen, YN Chen, HY Wang, ZT Liu, WB Frommer… - BMC biology, 2020 - Springer
Background Ammonium (NH 4 + ), a key nitrogen form, becomes toxic when it accumulates
to high levels. Ammonium transporters (AMTs) are the key transporters responsible for NH 4 …

Loss of Heterozygosity of FCY2 Leading to the Development of Flucytosine Resistance in Candida tropicalis

YN Chen, HJ Lo, CC Wu, HC Ko… - Antimicrobial agents …, 2011 - Am Soc Microbiol
As fluconazole resistance becomes an emerging issue for treating infections caused by
Candida tropicalis , searching for alternative becomes a prominent task. In the present study, 97 …

[HTML][HTML] Levels of evidence and study designs: A brief introduction to dermato-epidemiologic research methodology

YN Chen, CC Chi - Dermatologica Sinica, 2023 - journals.lww.com
Levels of evidence (LOE), also known as hierarchies of evidence, are determined primarily
by the inherent bias and validity of the study designs. Understanding LOE is a crucial …

[HTML][HTML] Concept of fluorescent transport activity biosensor for the characterization of the Arabidopsis NPF1. 3 activity of nitrate

YN Chen, CH Ho - Sensors, 2022 - mdpi.com
The NRT1/PTR FAMILY (NPF) in Arabidopsis (Arabidopsis thaliana) plays a major role as a
nitrate transporter. The first nitrate transporter activity biosensor NiTrac1 converted the dual-…

[PDF][PDF] CIPK15-mediated inhibition of NH4+ transport protects Arabidopsis from submergence

YN Chen, CH Ho - Heliyon, 2023 - cell.com
Ammonium (NH 4 + ) serves as a vital nitrogen source for plants, but it can turn toxic when it
accumulates in excessive amounts. Toxicity is aggravated under hypoxic/anaerobic …

[HTML][HTML] Fluorescent Biosensor Imaging of Nitrate in Arabidopsis thaliana

YN Chen, CH Ho - Bio-protocol, 2023 - ncbi.nlm.nih.gov
Nitrate (NO 3–) is an essential element and nutrient for plants and animals. Despite extensive
studies on the regulation of nitrate uptake and downstream responses in various cells, our …

In vivo visualization of nitrate dynamics using a genetically encoded biosensor

YN Chen, H Cartwright, CH Ho - bioRxiv, 2022 - biorxiv.org
Nitrate (NO 3 - ) uptake and distribution are critical to plant life. Although the upstream
regulation of nitrate uptake and downstream responses to nitrate in a variety of cells have been …