User profiles for Yeonjoo C. Hwang
Yeonjoo HwangBioinformatics Analyst, Emory University Verified email at emory.edu Cited by 250 |
[HTML][HTML] A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors
…, YC Hwang, C Cowdrey, C Moelders, C Schwarzer… - Nature cancer, 2023 - nature.com
BRAF V600E mutation confers a poor prognosis in metastatic colorectal cancer (CRC) despite
combinatorial targeted therapies based on the latest understanding of signaling circuitry. …
combinatorial targeted therapies based on the latest understanding of signaling circuitry. …
[PDF][PDF] Unbiased proteomic profiling uncovers a targetable GNAS/PKA/PP2A axis in small cell lung cancer stem cells
…, RS Levin, SM Moss, A He, J Sangodkar, YC Hwang… - Cancer Cell, 2020 - cell.com
Using unbiased kinase profiling, we identified protein kinase A (PKA) as an active kinase in
small cell lung cancer (SCLC). Inhibition of PKA activity genetically, or pharmacologically by …
small cell lung cancer (SCLC). Inhibition of PKA activity genetically, or pharmacologically by …
[HTML][HTML] Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies
The B cell leukemia/lymphoma 2 (BCL-2) inhibitor venetoclax is effective in chronic
lymphocytic leukemia (CLL); however, resistance may develop over time. Other lymphoid …
lymphocytic leukemia (CLL); however, resistance may develop over time. Other lymphoid …
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms
GKL Chan, S Maisel, YC Hwang, BC Pascual… - Elife, 2023 - elifesciences.org
Genetic alterations that activate protein kinase A (PKA) are found in many tumor types. Yet,
their downstream oncogenic signaling mechanisms are poorly understood. We used global …
their downstream oncogenic signaling mechanisms are poorly understood. We used global …
Oncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism
GKL Chan, S Maisel, YC Hwang, RRB Wolber, P Vu… - bioRxiv, 2021 - biorxiv.org
Genetic alterations that activate protein kinase A (PKA) signaling are found across many
tumor types, but their downstream oncogenic mechanisms are poorly understood. We used …
tumor types, but their downstream oncogenic mechanisms are poorly understood. We used …
A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAFV600E colorectal tumors
…, YC Hwang, C Cowdrey, C Moelders, C Schwarzer… - bioRxiv, 2022 - biorxiv.org
BRAF V600E mutation confers a poor prognosis in metastatic colorectal cancer (CRC) despite
combinatorial targeted therapies based on the latest understanding of signaling circuitry. …
combinatorial targeted therapies based on the latest understanding of signaling circuitry. …
Admission status conversion from voluntary into involuntary, is it illegal
JS Yoon, YH Joo, JH Ahn… - Journal of Korean …, 2016 - synapse.koreamed.org
Objectives The current Korean Mental Health Act (KMHA) indicates that a patient, who
voluntarily gave their permission for admission into a mental health facility, has the right to be …
voluntarily gave their permission for admission into a mental health facility, has the right to be …
[HTML][HTML] Integrated neuromorphic computing networks by artificial spin synapses and spin neurons
One long-standing goal in the emerging neuromorphic field is to create a reliable neural
network hardware implementation that has low energy consumption, while providing massively …
network hardware implementation that has low energy consumption, while providing massively …
A fuzzy multi-criteria approach to flood risk vulnerability in South Korea by considering climate change impacts
This study develops a framework to quantify the flood risk vulnerability in South Korea by
considering climate change impacts. On the basis of the concept of exposure-sensitivity-…
considering climate change impacts. On the basis of the concept of exposure-sensitivity-…
Larval chigger mites collected from small mammals in 3 provinces, Korea.
…, SHJ Song HyeonJe, CYJ Choi YeonJoo… - 2014 - cabidigitallibrary.org
A total of 9,281 larval chigger mites were collected from small mammals captured at
Hwaseong-gun, Gyeonggi-do (Province) (2,754 mites from 30 small mammals), Asan city, …
Hwaseong-gun, Gyeonggi-do (Province) (2,754 mites from 30 small mammals), Asan city, …