Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids

HA McNamara, Y Cai, MV Wagle, Y Sontani… - Science …, 2017 - science.org
Liver-resident CD8 + T cells are highly motile cells that patrol the vasculature and provide
protection against liver pathogens. A key question is: How can these liver CD8 + T cells be …

[PDF][PDF] Antibody feedback limits the expansion of B cell responses to malaria vaccination but drives diversification of the humoral response

…, AH Idris, HJ Sutton, R Vistein, BJ Flynn, Y Cai… - Cell host & …, 2020 - cell.com
Generating sufficient antibody to block infection is a key challenge for vaccines against
malaria. Here, we show that antibody titers to a key target, the repeat region of the Plasmodium …

[HTML][HTML] Diagnostic value of neutrophil gelatinase-associated lipocalin, cystatin C, and soluble triggering receptor expressed on myeloid cells-1 in critically ill patients …

X Dai, Z Zeng, C Fu, S Zhang, Y Cai, Z Chen - Critical care, 2015 - Springer
Introduction Neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys-C), and
soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) are novel diagnostic …

[HTML][HTML] APOE* E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease

…, A Chuah, C Tobon, D Rivera, A Villegas, Y Cai… - Molecular …, 2016 - nature.com
Alzheimer’s disease (AD) age of onset (ADAOO) varies greatly between individuals, with
unique causal mutations suggesting the role of modifying genetic and environmental …

Reaction-induced spreading of metal oxides onto surfaces of oxide supports during alcohol oxidation: Phenomenon, nature, and mechanisms

CB Wang, Y Cai, IE Wachs - Langmuir, 1999 - ACS Publications
Reaction-induced spreading of bulk metal oxides onto surfaces of oxide supports during
alcohol oxidation, a new phenomenon occurring at temperatures much lower than that required …

[HTML][HTML] Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats

…, Y Yang, M Lin, Y Cai, S Cai - Molecular Medicine …, 2017 - spandidos-publications.com
Previous studies have identified that dexmedetomidine (DEX) treatment can ameliorate the
acute lung injury (ALI) induced by lipopolysaccharide and ischemia-reperfusion. However, …

Ym1/2 promotes Th2 cytokine expression by inhibiting 12/15 (S)-lipoxygenase: identification of a novel pathway for regulating allergic inflammation

Y Cai, RK Kumar, J Zhou, PS Foster… - The Journal of …, 2009 - journals.aai.org
The Ym1/2 lectin is expressed abundantly in the allergic mouse lung in an IL-13-dependent
manner. However, the role of Ym1/2 in the development of allergic airways disease is …

[PDF][PDF] A natural peptide antigen within the plasmodium ribosomal protein RPL6 confers liver TRM cell-mediated immunity against malaria in mice

…, YC Chua, CM Jones, A Cozijnsen, V Mollard, Y Cai… - Cell host & …, 2020 - cell.com
Liver-resident memory CD8 + T (T RM ) cells remain in and constantly patrol the liver to elicit
rapid immunity upon antigen encounter and can mediate efficient protection against liver-…

Comparative roles of IL-4, IL-13, and IL-4Rα in dendritic cell maturation and CD4+ Th2 cell function

DC Webb, Y Cai, KI Matthaei… - The Journal of Immunology, 2007 - journals.aai.org
IL-4 and IL-13 play key roles in Th2 immunity and asthma pathogenesis. Although the function
of these cytokines is partially linked through their shared use of IL-4Rα for signaling, the …

Estrogen stimulates Th2 cytokine production and regulates the compartmentalisation of eosinophils during allergen challenge in a mouse model of asthma

Y Cai, J Zhou, DC Webb - International archives of allergy and …, 2012 - karger.com
Background: The observation that asthma becomes more prevalent following puberty in
females suggests estrogen potentiates the development of this disease. However, most studies …