Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway

X Ye, S Xu, Y Xin, S Yu, Y Ping, L Chen… - The Journal of …, 2012 - journals.aai.org
The invasion of malignant glioma cells into the surrounding normal brain tissues is crucial
for causing the poor outcome of this tumor type. Recent studies suggest that glioma stem-like …

[HTML][HTML] Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-for-discharge patient

…, Y Wang, H Mou, Q Guo, SC Yu, Y Ding, X Liu, YF Ping… - Cell research, 2020 - nature.com
SARS-CoV-2, a novel coronavirus and causing COVID-19, has given rise to a worldwide
pandemic. 1, 2 So far, tens of thousands of COVID-19 patients have been clinically cured and …

Isolation and characterization of cancer stem cells from a human glioblastoma cell line U87

S Yu, Y Ping, L Yi, Z Zhou, J Chen, X Yao, L Gao… - Cancer letters, 2008 - Elsevier
A variety of malignant cancers have been found to contain a subpopulation of stem cell-like
tumor cells, or cancer stem cells (CSCs). However, the existence of CSCs in U87, a most …

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell‐mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

Y Ping, X Yao, J Jiang, L Zhao, S Yu… - The Journal of …, 2011 - Wiley Online Library
Chemokines and their receptors are actively involved in inflammation, immune responses,
and cancer development. Here we report the detection of CD133 + glioma stem‐like cells (…

[HTML][HTML] Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth

Y Shi, YF Ping, W Zhou, ZC He, C Chen… - Nature …, 2017 - nature.com
Intense infiltration of tumour-associated macrophages (TAMs) facilitates malignant growth of
glioblastoma (GBM), but the underlying mechanisms remain undefined. Herein, we report …

[HTML][HTML] A cohort autopsy study defines COVID-19 systemic pathogenesis

…, YQ Ding, Q Mao, DY Zhang, SY Zhang, YF Ping… - Cell research, 2021 - nature.com
Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by dysfunction
of the lungs and extrapulmonary organs. However, the organotropism of SARS-CoV-2 and …

[PDF][PDF] Targeting glioma stem cell-derived pericytes disrupts the blood-tumor barrier and improves chemotherapeutic efficacy

…, RC Gimple, X Fang, Z Huang, K Zhai, SQ Ke, YF Ping… - Cell stem cell, 2017 - cell.com
The blood-tumor barrier (BTB) is a major obstacle for drug delivery to malignant brain
tumors such as glioblastoma (GBM). Disrupting the BTB is therefore highly desirable but …

[PDF][PDF] Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma

…, Q Li, M Liang, Y Jia, C Chen, S Xu, Y Shi, YF Ping… - Cancer Cell, 2023 - cell.com
Malignant gliomas are largely refractory to immune checkpoint blockade (ICB) therapy. To
explore the underlying immune regulators, we examine the microenvironment in glioma and …

Metastatic consequences of immune escape from NK cell cytotoxicity by human breast cancer stem cells

B Wang, Q Wang, Z Wang, J Jiang, SC Yu, YF Ping… - Cancer research, 2014 - AACR
Breast cancer stem-like cells (BCSC) are crucial for metastasis but the underlying mechanisms
remain elusive. Here, we report that tumor-infiltrating natural killer (NK) cells failed to limit …

[HTML][HTML] Pericytes augment glioblastoma cell resistance to temozolomide through CCL5-CCR5 paracrine signaling

…, B Wang, W Chen, S Wang, Y Shi, XW Bian, YF Ping - Cell research, 2021 - nature.com
Glioblastoma (GBM) is a prevalent and highly lethal form of glioma, with rapid tumor progression
and frequent recurrence. Excessive outgrowth of pericytes in GBM governs the ecology …