User profiles for Yi-Nan Zhang
Yi-Nan ZhangStaff Scientist, The Scripps Research Institute Verified email at scripps.edu Cited by 4635 |
Nanoparticle–liver interactions: Cellular uptake and hepatobiliary elimination
30–99% of administered nanoparticles will accumulate and sequester in the liver after
administration into the body. This results in reduced delivery to the targeted diseased tissue and …
administration into the body. This results in reduced delivery to the targeted diseased tissue and …
Thulium laser versus standard transurethral resection of the prostate: a randomized prospective trial
SJ Xia, J Zhuo, XW Sun, BM Han, Y Shao, YN Zhang - European urology, 2008 - Elsevier
OBJECTIVE: Thulium laser resection of the prostate-tangerine technique (TmLRP-TT) is a
transurethral procedure that uses thulium laser fiber to dissect whole prostatic lobes off the …
transurethral procedure that uses thulium laser fiber to dissect whole prostatic lobes off the …
The dose threshold for nanoparticle tumour delivery
Nanoparticle delivery to solid tumours over the past ten years has stagnated at a median of
0.7% of the injected dose. Varying nanoparticle designs and strategies have yielded only …
0.7% of the injected dose. Varying nanoparticle designs and strategies have yielded only …
Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities
YN Zhang, W Zhang, D Hong, L Shi, Q Shen… - Bioorganic & medicinal …, 2008 - Elsevier
Protein tyrosine phosphatase 1B is a key factor in the negative regulation of insulin pathway
and a promising target for treatment of diabetes and obesity. Herein, a series of competitive …
and a promising target for treatment of diabetes and obesity. Herein, a series of competitive …
Elimination pathways of nanoparticles
Understanding how nanoparticles are eliminated from the body is required for their
successful clinical translation. Many promising nanoparticle formulations for in vivo medical …
successful clinical translation. Many promising nanoparticle formulations for in vivo medical …
Engineering a highly elastic human protein–based sealant for surgical applications
Surgical sealants have been used for sealing or reconnecting ruptured tissues but often
have low adhesion, inappropriate mechanical strength, cytotoxicity concerns, and poor …
have low adhesion, inappropriate mechanical strength, cytotoxicity concerns, and poor …
Effect of removing Kupffer cells on nanoparticle tumor delivery
A recent metaanalysis shows that 0.7% of nanoparticles are delivered to solid tumors. This
low delivery efficiency has major implications in the translation of cancer nanomedicines, as …
low delivery efficiency has major implications in the translation of cancer nanomedicines, as …
A highly elastic and rapidly crosslinkable elastin‐like polypeptide‐based hydrogel for biomedical applications
Elastin‐like polypeptides (ELPs) are promising for biomedical applications due to their
unique thermoresponsive and elastic properties. ELP‐based hydrogels have been produced …
unique thermoresponsive and elastic properties. ELP‐based hydrogels have been produced …
The biology and ecology of the emerald ash borer, Agrilus planipennis, in China
XY Wang, ZQ Yang, JR Gould, YN Zhang… - Journal of insect …, 2010 - academic.oup.com
The biology, ecology, and life cycle of the emerald ash borer, Agrilus planipennis Fairmaire (Coleoptera:
Buprestidae), were studied using regular inspection in the forest and …
Buprestidae), were studied using regular inspection in the forest and …
Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity
Lymph node follicles capture and retain antigens to induce germinal centers and long-lived
humoral immunity. However, control over antigen retention has been limited. Here we …
humoral immunity. However, control over antigen retention has been limited. Here we …